Methylation differences in Alzheimer's disease neuropathologic change in the aged human brain
… methylation differences associated with Alzheimer's disease, we examined both
neuropathological scores as well as clinical measures (see Methods section “Neuropathological …
neuropathological scores as well as clinical measures (see Methods section “Neuropathological …
Epigenetic changes in Alzheimer's disease: decrements in DNA methylation
D Mastroeni, A Grover, E Delvaux, C Whiteside… - Neurobiology of …, 2010 - Elsevier
… methylation factors (ie, samples from different or overlapping subjects were evaluated for
each factor). Measurements were made by an investigator blind to the subjects’ experimental …
each factor). Measurements were made by an investigator blind to the subjects’ experimental …
Sex-specific DNA methylation differences in Alzheimer's disease pathology
… DNA methylation differences in AD neuropathology, we compared the FDR significant … [48]
that are annotated to Alzheimer's disease, many of which are antipsychotic medications …
that are annotated to Alzheimer's disease, many of which are antipsychotic medications …
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
… in Alzheimer’s disease entorhinal cortex. We demonstrate that previous estimates of DNA
hypermethylation in ANK1 in Alzheimer’s disease … percentage methylation difference between …
hypermethylation in ANK1 in Alzheimer’s disease … percentage methylation difference between …
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
G Shireby, EL Dempster, S Policicchio… - Nature …, 2022 - nature.com
… of AD neuropathology 10 , we and others have identified DNA methylation differences in …
including Parkinson’s disease (PD) 11,12,13,14,15,16,17,18,19 . A recent epigenome-wide …
including Parkinson’s disease (PD) 11,12,13,14,15,16,17,18,19 . A recent epigenome-wide …
Early epigenetic changes of Alzheimer's disease in the human hippocampus
I Blanco-Luquin, B Acha, A Urdánoz-Casado… - Epigenetics, 2020 - Taylor & Francis
… with neuropathological changes of pure AD. Correlation between DNA methylation levels
in … sites (DMPs) showed significant differences in DNA methylation levels in early-stage AD …
in … sites (DMPs) showed significant differences in DNA methylation levels in early-stage AD …
DNA methylation in the pathology of Alzheimer's disease: from gene to cognition
CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… that DNA methylation changes are observed in the EC of AD. … In a study investigating
DNA methylation differences in … of the neurotoxic Aβ42 and AD neuropathology. One-carbon …
DNA methylation differences in … of the neurotoxic Aβ42 and AD neuropathology. One-carbon …
Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex
… Lisa Bain from the MADC Neuropathology Core provided the tissue samples used in this
study. Susan Dagenais at the University of Michigan DNA Sequencing Core (PI: Robert Lyons) …
study. Susan Dagenais at the University of Michigan DNA Sequencing Core (PI: Robert Lyons) …
Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology
… Looking to the future, analyses of gene expression levels should be performed to facilitate
the interpretation of the DNA methylation differences we observe in HOXA. To conclude, this …
the interpretation of the DNA methylation differences we observe in HOXA. To conclude, this …
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex
… Alzheimer’s disease (AD) is a fatal neurodegenerative … Neuropathologically, AD is classified
according to spread of … -DMCGs with large methylation differences between young and old …
according to spread of … -DMCGs with large methylation differences between young and old …
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