Biofilm Formation by Cryptococcus neoformans

LR Martinez, A Casadevall - Microbiology spectrum, 2015 - Am Soc Microbiol
neoformans can form biofilms on medical devices that presumably contain polysaccharide
… would also interfere with cryptococcal biofilm formation. Addition of GXM-binding mAbs to C. …

Biofilm Formation by Cryptococcus neoformans Under Distinct Environmental Conditions

S Ravi, C Pierce, C Witt, FL Wormley - Mycopathologia, 2009 - Springer
neoformans was also cultured in DMEM at pH 7.4 and … cryptococcal biofilm formation at
pH 4.0 and ambient CO 2 to allow us to differentiate the effect of pH and/or CO 2 on biofilm

Cryptococcus neoformans Biofilm Formation Depends on Surface Support and Carbon Source and Reduces Fungal Cell Susceptibility to Heat, Cold, and UV Light

LR Martinez, A Casadevall - Applied and environmental …, 2007 - Am Soc Microbiol
… factors on cryptococcal biofilm formation and compared the susceptibilities of mature C. …
Since GXM release is necessary for cryptococcal biofilm formation, we purified GXM from C. …

Characterization of Phenotypic Switching in Cryptococcus neoformans Biofilms

LR Martinez, DC Ibom, A Casadevall, BC Fries - Mycopathologia, 2008 - Springer
neoformans infection, we hypothesized that biofilm formation may constitute a niche that
promotes phenotypic switching and therefore investigated the relationship of these events. …

Susceptibility of Cryptococcus neoformans Biofilms to Antifungal Agents In Vitro

LR Martinez, A Casadevall - Antimicrobial agents and …, 2006 - Am Soc Microbiol
… B and caspofungin interfered with C. neoformans biofilm formation involved capsular
polysaccharide release and adherence. Our results suggest that biofilm formation may diminish the …

Disarming Fungal Pathogens: Bacillus safensis Inhibits Virulence Factor Production and Biofilm Formation by Cryptococcus neoformans and Candida albicans

FL Mayer, JW Kronstad - MBio, 2017 - Am Soc Microbiol
… virulence factors, including formation of the antioxidant pigment melanin and production …
cryptococcal biofilm formation but had only modest inhibitory effects on already formed biofilms

The use of chitosan to damage Cryptococcus neoformans biofilms

LR Martinez, MR Mihu, G Han, S Frases, RJB Cordero… - Biomaterials, 2010 - Elsevier
… exoskeletons, to damage biofilms formed by the pathogenic fungus Cryptococcus … of
chitosan with yeast cells interfered with C. neoformans biofilm formation in vitro using the XTT …

Antibody-Mediated Immobilization of Cryptococcus neoformans Promotes Biofilm Formation

EJ Robertson, A Casadevall - Applied and environmental …, 2009 - Am Soc Microbiol
… Previously, we reported that antibody to GXM in solution could inhibit biofilm formation
-mediated immobilization of C. neoformans cells on cryptococcal biofilm formation has not …

EDTA inhibits biofilm formation, extracellular vesicular secretion, and shedding of the capsular polysaccharide glucuronoxylomannan by Cryptococcus neoformans

EJ Robertson, JM Wolf… - Applied and environmental …, 2012 - Am Soc Microbiol
… In conclusion, the cation chelator EDTA reduces biofilm formation by Cryptococcus
neoformans, an effect that that appears to result from the inhibition of the secretion of GXM-containing …

The Crucial Role of Biofilms in Cryptococcus neoformans Survival within Macrophages and Colonization of the Central Nervous System

L Aslanyan, DA Sanchez, S Valdebenito, EA Eugenin… - Journal of Fungi, 2017 - mdpi.com
… We describe the importance of the polysaccharide capsule in biofilm formation and survival
by C. neoformans … We evaluate the strategies in the context of biofilm function leading to C. …