… We also highlight recent progress in the development of inhibitors of NF-κB as
chemosensitizers for breast cancer. NF-κB … These observations prompted our laboratory …

… Increasing evidence of dysregulated NF-κB-associated pathways in various human breast
cancer cell lines and primary tumors supports a role for NF-κB in neoplastic transformation. …

… on the role of the NF B signaling pathways in the development and progression of breast
cancer and the validity of NF B as a potential target for breast cancer prevention and therapy. …

… Among them is the transcription factor NF-κB… NF-κB regulates the self-renewal of breast
cancer stem cells in a model of Her2-dependent tumourigenesis. We will describe here the NF-κB…

… the role of NF-κB in early embryonic development of mammary gland, two NFκB subunits,
RelA(… DNA binding activity of NFκB dimers increases during pregnancy, peaking at day 16 of …

… of NFκB is absolutely required for normal mammary gland development, NFκB involvment in
human breast cancers … (ER-negative) breast cancer. Newer clinical evidence now implicates …

… (E) Upon TNF-α stimulation, NF κB p65 subunit bind to CSN5 promoter and promotes its
transcription which subsequently induces its binding to PD-L1 and further deubiquitinates and …

… NF-κB in the cellular survival pathways of 2 isotypes of the Michigan Cancer Foundation (MCF-7)
breast … .13, 14 However, the role of NF-κB as it pertains to the evasion of apoptotic …

… IBC (Inflammatory Breast cancer) is a rare form of breast cancer with a particular phenotype.
New molecular targets are needed to improve the treatment of this rapidly fatal disease. …

… Our findings also support the potential of NF-κB inhibition for breast cancer treatment,
which was intensively studied by Umezawa’s group through both in vitro [46] and in vivo [27] …