MethylResolver—a method for deconvoluting bulk DNA methylation profiles into known and unknown cell contents
… Bulk tissue DNA methylation profiling has been used to … In silico deconvolution of cellular
fractions from bulk tissue data … subset fractions from methylation profiles of tumor admixtures. …
fractions from bulk tissue data … subset fractions from methylation profiles of tumor admixtures. …
Epigenetics: the DNA methylation profile of tissue-dependent and differentially methylated regions in cells
J Ohgane, S Yagi, K Shiota - Placenta, 2008 - Elsevier
… DNA methylation profile that consists of methylation patterns of numerous loci in the genome.
DNA methylation profiles are not associated with bulk DNA, … of DNA methylation profiles …
DNA methylation profiles are not associated with bulk DNA, … of DNA methylation profiles …
Integrative analyses of scRNA-seq, bulk mRNA-seq, and DNA methylation profiling in depressed suicide brain tissues
… between the methylated and transcript levels of differentially methylated CpG sites and …
for bulk mRNA-seq and DNA methylation profiling with scRNA-seq as the reference profiles. …
for bulk mRNA-seq and DNA methylation profiling with scRNA-seq as the reference profiles. …
Single-cell DNA methylation profiling: technologies and biological applications
ID Karemaker, M Vermeulen - Trends in biotechnology, 2018 - cell.com
… to facilitate single-cell DNA methylation profiling, their biological … further our understanding
of the biology of DNA methylation. … of DNA methylation, which are predominantly built on bulk …
of the biology of DNA methylation. … of DNA methylation, which are predominantly built on bulk …
LTBK-08. Inferring cell type and cell state composition in glioblastoma from bulk DNA methylation profiles using multi-omic single-cell analyses
D Silverbush, M Suva, V Hovestadt - Neuro-Oncology, 2022 - academic.oup.com
… their diagnosis with bulk DNA methylation profiling, which … method to deconvolute bulk
DNA methylation data and infer … bulk DNA methylation profiles of individual query samples. …
DNA methylation data and infer … bulk DNA methylation profiles of individual query samples. …
Methods in DNA methylation profiling
… was fragmented by restriction with MseI, a four-base cutter that cleaves bulk DNA into small
fragments (<200 bp). This endonuclease recognizes sequences that rarely occur within GC-…
fragments (<200 bp). This endonuclease recognizes sequences that rarely occur within GC-…
Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal …
… approach to bulk DNA methylation array data in a large set of newly profiled samples (n =
741) as well as samples from external data sources (n = 3311) of methylation-defined glial and …
741) as well as samples from external data sources (n = 3311) of methylation-defined glial and …
ARIC: accurate and robust inference of cell type proportions from bulk gene expression or DNA methylation data
… We proposed ARIC as a unified proportion deconvolution method for bulk data including
gene expression and DNA methylation. ARIC outperforms other methods with high accuracy …
gene expression and DNA methylation. ARIC outperforms other methods with high accuracy …
Profiling genome-wide DNA methylation
… The first WGBS in 2008 reported the composition of CpG, CHG and CHH methylation in
the Arabidopsis genome, the bulk methylation level within each context, and the global …
the Arabidopsis genome, the bulk methylation level within each context, and the global …
Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons
… We found significantly lower DNA methylation levels in NeuN+ samples compared with bulk
… We found a lower global DNA methylation in neuronal nuclei compared with bulk cortex. It …
… We found a lower global DNA methylation in neuronal nuclei compared with bulk cortex. It …
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