DNA methylation and cancer
M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
… of certain tumor-suppressor genes occurs as a consequence … of genes silenced by DNA
methylation in different cancer types. … Apart from DNA methylation alterations in promoter regions …
methylation in different cancer types. … Apart from DNA methylation alterations in promoter regions …
DNA methylation and cancer
PM Das, R Singal - Journal of clinical oncology, 2004 - ascopubs.org
… These events cause critical loss of gene activity and thereby predispose to cancer. DNA
methylation can modify the gene activity without changing the gene sequence and has been …
methylation can modify the gene activity without changing the gene sequence and has been …
DNA methylation and cancer
RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
… in human cancer cells and primary tumors are summarized in Table 1. The different classes
of genes that are silenced by DNA methylation include tumor suppressor genes, genes that …
of genes that are silenced by DNA methylation include tumor suppressor genes, genes that …
DNA methylation of cancer genome
… silencing of tumor suppressor genes that play critical … DNA methylation in cancer cells and
summarize recent advancements of techniques that facilitate genome-wide study of the cancer …
summarize recent advancements of techniques that facilitate genome-wide study of the cancer …
DNA methylation and cancer
PW Laird, R Jaenisch - Human molecular genetics, 1994 - academic.oup.com
… It is essential to our understanding of the role of DNA methylation in cancer to find out whether
the changes seen in DNA methylation patterns and MTase expression contribute to or are …
the changes seen in DNA methylation patterns and MTase expression contribute to or are …
The role of DNA methylation in cancer genetics and epigenetics
PW Laird, R Jaenisch - Annual review of genetics, 1996 - annualreviews.org
… silencing of tumor suppressor genes by DNA methylation. The thirddevelopment has been
… to manipulate DNAmethylation levels. These studies demonstrate that DNA methylation …
… to manipulate DNAmethylation levels. These studies demonstrate that DNA methylation …
The role of DNA methylation in cancer development.
MW Luczak, PP Jagodziński - Folia histochemica et …, 2006 - journals.viamedica.pl
… effect of mutations of various tumor suppressor genes (TSGs) or … DNA methylation that
include hypermethylation and hypomethylation of promoter or first exon of cancer-related genes. …
include hypermethylation and hypomethylation of promoter or first exon of cancer-related genes. …
DNA methylation and cancer
PC Taberlay, PA Jones - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
… the epigenetic silencing of genes in concert with DNA methylation in cancer cells. In normal
… interfering with the process of gene expression. DNA methylation and the acquisition of …
… interfering with the process of gene expression. DNA methylation and the acquisition of …
DNA methylation and cancer
PA Jones - Oncogene, 2002 - nature.com
… 9 methylation is also necessary for some DNA methylation in … , suggesting ways in which
DNA methylation patterns may be … carcinogenesis where DNA methylation patterns become …
DNA methylation patterns may be … carcinogenesis where DNA methylation patterns become …
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