Determining the effect of DNA methylation on gene expression in cancer cells
… gene expression pattern characteristics of all human cancers. … on DNA methylation and gene
expressions in cancer. Then … of DNA methylation and gene expression in 30 breast cancer …
expressions in cancer. Then … of DNA methylation and gene expression in 30 breast cancer …
Use of DNA methylation for cancer detection: promises and challenges
J Zhu, X Yao - The international journal of biochemistry & cell biology, 2009 - Elsevier
… detection and prognostic prediction have been initiated since the pursuit of cancer
genetics began several decades ago. It was until recently that the FDA had approved the first …
genetics began several decades ago. It was until recently that the FDA had approved the first …
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2
KM McGarvey, E Greene, JA Fahrner, T Jenuwein… - Cancer research, 2007 - AACR
… methylation. However, we show that whereas basally expressed target cancer genes with
minimal DNA methylation … , densely DNA hypermethylated and silenced genes retain their …
minimal DNA methylation … , densely DNA hypermethylated and silenced genes retain their …
Breast cancer epigenetics: from DNA methylation to microRNAs
J Veeck, M Esteller - Journal of mammary gland biology and neoplasia, 2010 - Springer
… inactivated genes in cancer is constantly increasing, the basic mechanisms underlying
aberrant DNA methylation as well as the selection of genes that become methylated are only …
aberrant DNA methylation as well as the selection of genes that become methylated are only …
DNA methylation and genetic aberrations in gastric cancer
G Usui, K Matsusaka, Y Mano, M Urabe, S Funata… - Digestion, 1964 - karger.com
… are methylated in the whole promoter regions by EBV infection, whereas DNA
methylation-resistant genes methylated … Besides, a comprehensive DNA methylation analysis …
methylation-resistant genes methylated … Besides, a comprehensive DNA methylation analysis …
DNA methylation pattern as important epigenetic criterion in cancer
M Ghavifekr Fakhr, M Farshdousti Hagh… - Genetics research …, 2013 - Wiley Online Library
… changes may alter the gene expression. As … gene expression are DNA methylation and
histone changes [33]. Several changes in the pattern of DNA methylation and silencing the genes …
histone changes [33]. Several changes in the pattern of DNA methylation and silencing the genes …
DNA methylation and colorectal cancer
H Ashktorab, H Brim - Current colorectal cancer reports, 2014 - Springer
… also the identification of methylated genes that might influence … , we discuss DNA methylation
of CRC-associated genes and … cancer gene, was only found to display low methylation in …
of CRC-associated genes and … cancer gene, was only found to display low methylation in …
DNA methylation profiling: an emerging paradigm for cancer diagnosis
A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
… and gene body demethylation correlate with gene silencing (12–14). However, the effect
of DNA methylation on cancer gene … Patterns of DNA methylation are tissue specific (16), a …
of DNA methylation on cancer gene … Patterns of DNA methylation are tissue specific (16), a …
Pancancer analysis of DNA methylation-driven genes using MethylMix
… of a cancer gene as hypo- or hyper-methylated … of DNA methylation in over 4,000 tumors
and across 12 cancer sites from TCGA using a novel computational approach. DNA methylation …
and across 12 cancer sites from TCGA using a novel computational approach. DNA methylation …
DNA methylation: past, present and future directions
KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
… Such studies are likely to yield major contributions to understanding the role of DNA
methylation in cancer and, since methylation changes are reversible, may also lead to the …
methylation in cancer and, since methylation changes are reversible, may also lead to the …