DNA methylation and cancer therapy
M Szyf - Drug Resistance Updates, 2003 - Elsevier
… However, recent data suggests that inhibition of DNA methylation might have untoward …
DNA methylation in cancer, proposes a unified hypothesis on the relative roles of increased DNA …
DNA methylation in cancer, proposes a unified hypothesis on the relative roles of increased DNA …
DNA methylation as a therapeutic target in cancer
JPJ Issa - Clinical Cancer Research, 2007 - AACR
… Targeting DNA methylation for cancer therapy has had a rocky history. The first reports on
DNA methylation changes in cancer described global loss of methylation, which has been …
DNA methylation changes in cancer described global loss of methylation, which has been …
Cancer epigenomics: implications of DNA methylation in personalized cancer therapy
M Toyota, H Suzuki, T Yamashita, K Hirata… - Cancer …, 2009 - Wiley Online Library
… of epigenetic alterations such as DNA methylation in predicting the efficacy of
chemotherapeutic drugs in the treatment of cancer. Role of DNA methylation in carcinogenesis …
chemotherapeutic drugs in the treatment of cancer. Role of DNA methylation in carcinogenesis …
[HTML][HTML] DNA methylation: its role in cancer development and therapy
C Kurkjian, S Kummar, AJ Murgo - Current problems in cancer, 2008 - ncbi.nlm.nih.gov
… and cancer. In a series of 154 healthy volunteers and 72 patients with gastric cancer, methylation
… 14 Among the healthy volunteers, the extent of DNA methylation was 5.4-to 303-times …
… 14 Among the healthy volunteers, the extent of DNA methylation was 5.4-to 303-times …
DNA methylation profiles in cancer diagnosis and therapeutics
Y Pan, G Liu, F Zhou, B Su, Y Li - Clinical and experimental medicine, 2018 - Springer
… DNA methylation biomarkers for diagnosis of cancer was provided. DNA methylation in
cancer … Exploring the possible methods of DNA methylation is necessary for cancer diagnosis. …
cancer … Exploring the possible methods of DNA methylation is necessary for cancer diagnosis. …
Emerging DNA methylation inhibitors for cancer therapy: challenges and prospects
A Gonzalez-Fierro… - Expert Review of …, 2019 - Taylor & Francis
… DNA methylation in cancer. Global hypomethylation in some models promotes and in other
models protects cancer … The complexity of DNA methylation makes hard to arrive at educated …
models protects cancer … The complexity of DNA methylation makes hard to arrive at educated …
[HTML][HTML] Role of DNA methylation in the resistance to therapy in solid tumors
S Romero-Garcia, H Prado-Garcia… - Frontiers in …, 2020 - frontiersin.org
… types, such as breast, colon, and lung cancer, among other solid … of methylated region-specific
DNA that can be used to predict the treatment outcome in response to anti-cancer therapy. …
DNA that can be used to predict the treatment outcome in response to anti-cancer therapy. …
DNA methylation: an epigenetic pathway to cancer and a promising target for anticancer therapy
J Worm, P Guldberg - Journal of oral pathology & medicine, 2002 - Wiley Online Library
… play an important role in many cancers. This review concerns DNA methylation as an
epigenetic … and maintenance of DNA methylation in normal cells (ii) DNA methylation-mediated …
epigenetic … and maintenance of DNA methylation in normal cells (ii) DNA methylation-mediated …
DNA methylation and cancer therapy: new developments and expectations
M Esteller - Current opinion in oncology, 2005 - journals.lww.com
… having genetic causes, cancer can also be considered an epigenetic disease. The main
epigenetic modification is DNA methylation, and patterns of aberrant DNA methylation are now …
epigenetic modification is DNA methylation, and patterns of aberrant DNA methylation are now …
The role of DNA methylation in cancer development.
MW Luczak, PP Jagodziński - Folia histochemica et …, 2006 - journals.viamedica.pl
… DNA methylation in cancer cells is a new field of investigation in carcinogenesis. We believe
that epigenetic cancer diagnostic and therapy … Usage of this drug in cancer therapy exhibits …
that epigenetic cancer diagnostic and therapy … Usage of this drug in cancer therapy exhibits …
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