Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

M Jeffries, M Dozmorov, Y Tang, JT Merrill, JD Wren… - Epigenetics, 2011 - Taylor & Francis
DNA methylation in lupus T cells, we performed a genome-wide DNA methylation study in
CD4 + T cells in … Cytosine methylation was quantified in 27,578 CG sites located within the …

Genome‐wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome

N Altorok, P Coit, T Hughes, KA Koelsch… - Arthritis & …, 2014 - Wiley Online Library
… of T cells, and demonstrating that interferon (IFN)–regulated genes in naive CD4+ T cells
a genome-wide DNA methylation study in naive CD4+ T cells from patients with primary SS …

Impaired DNA methylation and its mechanisms in CD4+ T cells of systemic lupus erythematosus

Y Zhang, M Zhao, AH Sawalha, B Richardson… - Journal of autoimmunity, 2013 - Elsevier
… and DNA hydroxymethylation have been proposed as potential mechanisms leading to DNA
… In this review, we summarize current understanding of T cell DNA methylation changes and …

Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients

R Pitaksalee, AN Burska, S Ajaib, J Rogers… - Clinical …, 2020 - Springer
cell-specific changes in DNA methylation in early RA in circulating leukocytes. These differences
are both qualitative (for example the excess of hypermethylation in memory T-cells) and …

Phenotypic characteristics of aged CD4+ CD28null T lymphocytes are determined by changes in the whole‐genome DNA methylation pattern

B Suarez‐Álvarez, RM Rodríguez, K Schlangen… - … Cell, 2017 - Wiley Online Library
… 296 differentially methylated genes related to defects in TCR signaling, cellT cells. Our
results indicate that specific changes in DNA methylation dynamics in conventional CD4 + T cells

Genome-wide DNA methylation patterns in CD4+ T cells from Chinese Han patients with rheumatoid arthritis

S Guo, Q Zhu, T Jiang, R Wang, Y Shen… - Modern …, 2017 - academic.oup.com
DNA methylation in RA CD4T cells, we performed a genome-wide DNA methylation study in
CD4 + T cells in … Cytosine methylation status was quantified with Illumina methylation 450K …

Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation

HK Komori, T Hart, SA LaMere, PV Chew… - The Journal of …, 2015 - journals.aai.org
… activation compared with naive cells. These reveal … cells and putatively regulated by DNA
methylation. These findings define a DNA methylation signature unique to memory CD4 T cells

Profiling of CD4+ T cells with epigenetic immune lineage analysis

PCJ Janson, LB Linton, E Ahlén Bergman… - The Journal of …, 2011 - journals.aai.org
… isolated human CD4 + T cells on any T cell effector axis based on specific CpG methylation
of cytokine … In this study, we first demonstrate the importance of DNA methylation for the Th17 …

DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis

V Natoli, A Charras, SR Hofmann, S Northey… - Frontiers in …, 2023 - frontiersin.org
… disease-associated DNA methylation patterns in CD4 + T-cells from psoriasis and PsA …
CD4 + T-cells were separated through FACS sorting, and DNA methylation profiling was …

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus

P Renauer, P Coit, MA Jeffries, JT Merrill… - Lupus science & …, 2015 - lupus.bmj.com
DNA hypomethylation in naïve CD4+ T cells.1 In this study, we explore DNA methylation
changes in naïve CD4+ T cells … discoid rash to identify patterns of epigenetic susceptibility that …