Dynamic DNA methylation across diverse human cell lines and tissues

KE Varley, J Gertz, KM Bowling, SL Parker… - Genome …, 2013 - genome.cshlp.org
… -base resolution DNA methylation profiling on a diverse collection of 82 human cell lines
and … This study provides an atlas of DNA methylation across diverse and well-characterized …

DNA methylation and the expanding epigenetics of T cell lineage commitment

CB Wilson, KW Makar, M Shnyreva… - Seminars in immunology, 2005 - Elsevier
… T cells and Th2 cytokine expression in Th1 and CD8 T cells, … and KIR gene expression in
NK cells. However, most of our … importance of DNA methylation in memory cell lineage fidelity …

Systematic DNA methylation analysis of multiple cell lines reveals common and specific patterns within and across tissues of origin

X Yang, X Shao, L Gao, S Zhang - Human molecular genetics, 2015 - academic.oup.com
… the DNA methylation data across 54 human cell lines, we identified 35 276 local DNA
methylation … , cell lineage-specific and cell line-specific DNA methylation patterns in 54 diverse …

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

LE Reinius, N Acevedo, M Joerink, G Pershagen… - PloS one, 2012 - journals.plos.org
… the cell types according to their lineageDNA methylation between lymphoid and myeloid
cells and identified many CpG sites that were differentially methylated between the purified cell

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

M Monk, M Boubelik, S Lehnert - Development, 1987 - journals.biologists.com
… Fetal germ cell DNA is markedly undermethylated and we favour the idea that the germ
lineage is set aside before the occurrence of extensive methylation of DNA in fetal precursor cells

DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages

DM Maatouk, LD Kellam, MRW Mann, H Lei, E Li… - 2006 - journals.biologists.com
cell differentiation events. To investigate a possible role for DNA methylation changes in germ
cell … Here, we show that the postmigratory germ cell-specific genes Mvh, Dazl and Scp3are …

Tracing human stem cell lineage during development using DNA methylation

LA Salas, JK Wiencke, DC Koestler, Z Zhang… - Genome …, 2018 - genome.cshlp.org
… In conclusion, we defined and applied a DNA methylation signature common … cells and
have shown that this signature traces the lineage of cells and informs the study of stem cell

[PDF][PDF] DNA methylation and its role in the trophoblast cell lineage

S Tanaka, MO Nakanishi, K Shiota - Int J Dev Biol, 2014 - academia.edu
… Thus, DNA methylation works to fix cell lineage restriction … involved in DNA methylation-mediated
cell lineage restriction. … of trophoblast lineage markers in ES cells under differentiation …

DNA methylation in extraembryonic lineages of mammals

JP Sanford, VM Chapman, J Rossant - Trends in Genetics, 1985 - cell.com
… derivation of cell lineages and the DNA methylation patterns in extraernbryonic cell lineages,
… the CCGG sites in the 2- to 8-cell cleaving embryos were methylated. Trophoblast and ICM …

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages

ML Sellars, JR Huh, K Day, PD Issuree, C Galan… - Nature …, 2015 - nature.com
… in CD8 + T cells was stable, we also assessed DNA methylation after multiple cell divisions.
Wild-type CD4 + and CD8 + cells and Cd4 S4Δ/S4Δ CD4 + CD8 + cells that had undergone …