… widespread resetting of cancer-specific DNA methylation marks in GNS cells. This enabled
us to assess the relative contribution of the cancer epigenome to malignant cellular behavior. …

… DNA methylation plays an important role in epigenetic programming by silencing … genes,
thus establishing a cellular memory that defines both cell lineage and cell type. By contrast, …

… DNA hypomethylation after commitment to the B-cell lineage had been established.
Addition of a Gt(ROSA) allele carrying an inducible loxP-STOP-loxP-EYFP (enhanced yellow …

… sperm cells (SCs) and a vegetative cell (VC). However, when and how the DNA methylation
of … Here we investigate the DNA methylation (5 mC) dynamics of SC lineage and the VC in …

… cell division, similar to a stem cell niche (11), stem cell lineage extinction was balanced by
stem cell lineage expansion such that total stem cell numbers per gland were constant. To …

… To investigate cell-type-specific DNA methylation patterns, we … precursor cells (NPCs) and
various primary cell populations (… levels across the Olig1/Olig2 neural-lineage transcription …

… maintenance enzymes, and which are changed in particular cell lineages by switching …
is related to DNA methylation, and that the pattern of cytosine methylation is heritable (4-6). …

… We suggest that DNAme turnover can also contribute to stochasticity, symmetry breaking
and the emergence of different cell lineages from the same pool of stem cells upon exposure to …

… of DNA methylation during cell division is essential for repression of a cell lineage determina…
We hypothesized that key determinants of the a cell lineage were methylated and repressed …

… methylated region in undifferentiated trophoblast stem cells with repressed Ddah2. Our
data suggest that DNA methylation-… and thus is important even in trophoblast cell lineage. …