… in defining cell types, and is disrupted in many diseases. We describe large-scale single-base
resolution DNA methylation profiling on a diverse collection of 82 human cell lines and …

… in the cultured cancer cell lines has any effect on DNA methylation patterns, we studied four
… our collection of human cancer cell lines. The four germ-line variants analyzed are relatively …

… differences in the global methylation levels between cell lines; the CG methylation level is
highest … A similar trend is also observed for non-CG methylation. The differences in methylation …

… DNA methylation between cell lines and tumors, using a two-sample t-test to compare DNA
methylation … Only the 1,110 CpG sites that met a minimal level of variability in methylation …

… in methylation can affect transcription and phenotypic variation [1], but the source of variation
in DNA methylation … Substantial evidence of inter-individual variation in DNA methylation …

… DNA methylation profiling study, which includes the quantitative analysis of >500 genomic
target regions representing >400 genes in 59 cell lines … -related DNA methylation changes …

… Within this group, a large cluster consisted almost exclusively of SCLC cell lines. Our
results show that DNA methylation patterns differ between NSCLC and SCLC cell lines and …

… DNA suggesting that epigenetics plays an important role in tumorigenesis. The potent and
specific inhibitor of DNA methylation, 5-… genes in human tumor cell lines. These genes may be …

… was restored by treatment of a human bladder cancer cell line with 5-Aza-CdR, suggesting
… also be silenced by DNA methylation. One important function of DNA methylation may be to …

… DNA METHYLATION PATTERNS IN CELL LINES Analysis of endogenous genes and of …
in somatic cells in culture suggests that DNA methylation patterns are stable in such lines. …