Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications
V Santini, HM Kantarjian, JP Issa - Annals of internal medicine, 2001 - acpjournals.org
Methylation of DNA is a biochemical modification that can … of abnormalities in DNA methylation
may therefore restore the … rationale for targeting aberrant methylation in cancer therapy …
may therefore restore the … rationale for targeting aberrant methylation in cancer therapy …
Tobacco smoking leads to extensive genome-wide changes in DNA methylation
S Zeilinger, B Kühnel, N Klopp, H Baurecht… - PloS one, 2013 - journals.plos.org
… change of 6.1. Upon smoking cessation, the expression of this gene fell extensively, but
changes … which corresponds to the progress of DNA methylation changes we were able to detect …
changes … which corresponds to the progress of DNA methylation changes we were able to detect …
Changes in DNA methylation patterns in subjects exposed to low-dose benzene
… exposure on DNA methylation using peripheral blood DNA from … to evaluate (a) DNA
methylation changes in AluI and long … of genome-wide methylation, (b) promoter methylation of …
methylation changes in AluI and long … of genome-wide methylation, (b) promoter methylation of …
Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells
A Di Francesco, B Arosio, A Falconi… - Brain, behavior, and …, 2015 - Elsevier
… Changes in epigenetic marks may help explain the late … DNA methylation by luminometric
methylation assay, a quantitative measurement of genome-wide DNA methylation, on DNA …
methylation assay, a quantitative measurement of genome-wide DNA methylation, on DNA …
DNA methylation and healthy human aging
… Changes in DNA methylation occur throughout the lifetime, beginning at conception. Early
studies assessing levels of DNA methylation … that gradual change in DNA methylation occurs …
studies assessing levels of DNA methylation … that gradual change in DNA methylation occurs …
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… Our results indicate that levels of 5mC and 5hmC positively correlate with Aβ, NFTs, and
ubiquitin loads found in MTG suggesting that increases in DNA methylation and …
ubiquitin loads found in MTG suggesting that increases in DNA methylation and …
Impact of aging on DNA methylation
B Richardson - Ageing research reviews, 2003 - Elsevier
… DNA methylation, the changes in DNA methylation can also impact on aging. This review
summarizes current evidence for changes in the methylation … altered DNA methylation patterns. …
summarizes current evidence for changes in the methylation … altered DNA methylation patterns. …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… in gene expression without a change in nucleotide sequence) phenomena. Although extensive
in plants and mammals, the absence of detectable DNA methylation in some eukaryotes …
in plants and mammals, the absence of detectable DNA methylation in some eukaryotes …
Rapid DNA methylation changes after exposure to traffic particles
A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
… changes in DNA methylation in human subjects has not been investigated. … DNA methylation
in LINE-1 and Alu repetitive elements and the time-related patterns of DNA methylation …
in LINE-1 and Alu repetitive elements and the time-related patterns of DNA methylation …
Extensive changes in DNA methylation are associated with expression of mutant huntingtin
… been shown to undergo methylation changes in response to … change in methylation, we
identify AP-1 and SOX2 as transcriptional regulators associated with DNA methylation changes, …
identify AP-1 and SOX2 as transcriptional regulators associated with DNA methylation changes, …