Altered mode of allelic replication accompanied by aneuploidy in peripheral blood lymphocytes of prostate cancer patients

ZA Dotan, A Dotan, J Ramon… - International journal of …, 2004 - Wiley Online Library
… Our results are in agreement with data showing chromosomal aberrations in peripheral … of
DNA methyltransferases were found to cooperatively maintain DNA hypermethylation patterns

Making it or breaking it: DNA methylation and genome integrity

A Sriraman, TK Debnath, B Xhemalce… - Essays in …, 2020 - portlandpress.com
… Centrosomal defects are observed in breast cancer and result in aneuploidy due to chromosomal
instability (CIN) [130]. Since p53 signaling axis is often compromised, p21, its bonafide …

BRCA1 Promoter Methylation in Sporadic Breast Cancer Is Associated with Reduced BRCA1 Copy Number and Chromosome 17 Aneusomy

M Wei, TA Grushko, J Dignam, F Hagos, R Nanda… - Cancer research, 2005 - AACR
methylation heterogeneity due to incomplete methylation of the CpG island and to examine
the relationship between patterns of DNA methylation… expression and DNA aneuploidy. …

Allele-specific replication associated with aneuploidy in blood cells of patients with hematologic malignancies

A Korenstein-Ilan, A Amiel, S Lalezari, M Lishner… - Cancer genetics and …, 2002 - Elsevier
pattern of replication in the patients' cells by introducing an inhibitor of DNA methylation. It
… in an increased rate of aneuploidy (losses and gains of whole chromosomes), was reported …

Noninvasive prenatal detection of fetal chromosomal aneuploidies by maternal plasma nucleic acid analysis: a review of the current state of the art

YMD Lo - BJOG: An International Journal of Obstetrics & …, 2009 - Wiley Online Library
… Furthermore, different tissues may have a tissue-specific pattern of DNA methylation. … to
develop fetal DNA markers based on differential DNA methylation patterns between maternal …

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

T Hinoue, DJ Weisenberger, CPE Lange… - Genome …, 2012 - genome.cshlp.org
… HM27 DNA methylation assay to investigate DNA methylation-… gene promoter DNA methylation
of all 14,495 consensus coding DNA … on either the X or Y chromosome. We analyzed the …

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidies by maternal plasma nucleic acid analysis

YM Dennis Lo, RWK Chiu - Clinical chemistry, 2008 - academic.oup.com
… The extension of such a restriction enzyme–based approach to markers exhibiting a
reverse pattern of differential DNA methylation, namely hypomethylated in the placenta and …

[HTML][HTML] The constant variation: DNA methylation changes during preimplantation development

T Arányi, A Páldi - FEBS letters, 2006 - Elsevier
… applied on metaphase chromosomes the global topology of DNA methylation is visualized
[… on the topology of global DNA methylation at the single chromosomal level. In addition to …

Identification of differentially methylated genes in first-trimester placentas with trisomy 16

EN Tolmacheva, SA Vasilyev, TV Nikitina… - Scientific Reports, 2022 - nature.com
aneuploidy in first-trimester miscarriages. The present study identified changes in DNA
methylation … 1 , which indicates that chromosomal aneuploidy has a harmful pleiotropic effect. The …

Global analysis of gene expression in response to whole-chromosome aneuploidy in hexaploid wheat

A Zhang, N Li, L Gong, X Gou, B Wang, X Deng… - Plant …, 2017 - academic.oup.com
Aneuploidy also frequently is associated with plant … types of whole-chromosome aneuploidy
of hexaploid wheat (… impact of aneuploidy on genome-, subgenome-, and chromosome-wide …