… activation of NFAT activity in CLL cells. This comprehensive DNA methylation analysis
will further our understanding of the epigenetic contribution to cellular dysfunction in CLL. …

… Second, there are different techniques to perform large-scale methylation analysis and is
probable that our study may only provide a partial view of the epigenome of the …

… lymphocytic leukemia (CLL). The analysis was based on DNA hydrolysis followed by …
We analyzed potential correlations between DNA methylation levels and numerous patient …

Aims: B-cell chronic lymphocytic leukemia (CLL) is a … CLL, like other cancers, can be affected
by epigenetic … -based study was initiated to determine DNA methylation in CLL cases with a …

… Next, we proceeded to methylation analysis at the individual case level. In addition to the
DNA methylation changes observed after relapse, we also investigated the alterations which …

… Microarray-based DNA methylation assay … In summary, our study revealed that the DNA
methylation pattern was altered across the genome in CLL patients. Differentially expressed …

… Using high-resolution 450K arrays, we provide the most comprehensive DNA
methylation study of CLL to date, analyzing paired diagnostic/follow-up samples from IGHV-mutated/…

… This approach of elucidating intrasample heterogeneity has been used previously in
conjunction with the HELP genome-wide methylation assay (28). Here, intrasample …

… this phenomenon at the genome-wide level, we did a comprehensive analysis of our DNA
methylation … The Infinium methylation assay was carried out as described previously 15,35 . …

… Our dual-enzyme global methylation study shows that CLL is characterized by widespread
… regulated, at least in part, by DNA methylation, and that expression levels can be modulated …