Large-scale analysis of DNA methylation in chronic lymphocytic leukemia
FB Rahmatpanah, S Carstens, SI Hooshmand… - …, 2009 - Taylor & Francis
… methylated in those with high CD38 expression. Conclusion: This study demonstrates that
CLL is affected by CpG island methylation … others show similar methylation patterns across all …
CLL is affected by CpG island methylation … others show similar methylation patterns across all …
Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets
LJ Rush, A Raval, P Funchain, AJ Johnson, L Smith… - Cancer research, 2004 - AACR
… methylation in chronic lymphocytic leukemia (CLL). To provide a baseline estimate of global
aberrant methylation … Restriction Landmark Genomic Scanning on 10 CLL samples. Two …
aberrant methylation … Restriction Landmark Genomic Scanning on 10 CLL samples. Two …
Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia
L Pei, JH Choi, J Liu, EJ Lee, B McCarthy, JM Wilson… - Epigenetics, 2012 - Taylor & Francis
… -wide DNA methylation analysis in CD19 + B-cells from chronic lymphocytic leukemia (CLL) …
The methylation status of 1.8–2.3 million CpGs in the CLL genome was determined; about …
The methylation status of 1.8–2.3 million CpGs in the CLL genome was determined; about …
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
… intratumor heterogeneity and evolution of DNA methylation and genetic aberrations in
chronic lymphocytic leukemia (CLL). CLL cases exhibit vast interpatient differences in intratumor …
chronic lymphocytic leukemia (CLL). CLL cases exhibit vast interpatient differences in intratumor …
Uncovering the DNA methylome in chronic lymphocytic leukemia
N Cahill, R Rosenquist - Epigenetics, 2013 - Taylor & Francis
… methylation profiles; we recognize DNA methylation of a … in CLL, and acknowledge the role
of DNA methylation outside of … Today, the significance and timing of altered DNA methylation …
of DNA methylation outside of … Today, the significance and timing of altered DNA methylation …
CpG island methylation patterns in chronic lymphocytic leukemia
B Seeliger, S Wilop, R Osieka, O Galm… - Leukemia & …, 2009 - Taylor & Francis
… -specific polymerase chain reaction the CpG island methylation status of 15 well-… in 32
patients with CLL. Aberrant methylation in the sample of patients with CLL was shown for secreted …
patients with CLL. Aberrant methylation in the sample of patients with CLL was shown for secreted …
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
… By comparing normal B cells to malignant B cells from 268 patients with chronic lymphocytic
leukemia (CLL), we showed that tumors derive largely from a continuum of maturation states …
leukemia (CLL), we showed that tumors derive largely from a continuum of maturation states …
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
WG Tong, WG Wierda, E Lin, SQ Kuang, BN Bekele… - Epigenetics, 2010 - Taylor & Francis
… of aberrant DNA methylation in chronic lymphocytic leukemia (CLL) using methylated CpG
… We identified 280 potential targets of aberrant DNA methylation in CLL. These genes were …
… We identified 280 potential targets of aberrant DNA methylation in CLL. These genes were …
Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia
… the methylation levels of repetitive DNA elements in chronic lymphocytic leukemia (CLL), their
… A quantitative bisulfite-PCR Pyrosequencing method was used to evaluate methylation of …
… A quantitative bisulfite-PCR Pyrosequencing method was used to evaluate methylation of …
Epigenetics in chronic lymphocytic leukemia
… , genome-wide methylation studies have further emphasized the role of DNA … methylation
machinery in CLL. Data from global methylation analysis in different tumors and leukemias by …
machinery in CLL. Data from global methylation analysis in different tumors and leukemias by …
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