[HTML][HTML] Delving into the origin of destructive inflammation in COVID-19: a betrayal of natural host defense peptides?

R Garcia-Fandino, A Pineiro - Frontiers in Immunology, 2021 - frontiersin.org
… by COVID-19, and in the fact that our endogenous antimicrobial peptides (AMPs) are
sensitive to the membrane composition of pathogenic agents, we propose that such destructive

COVID19: A case for inhibiting NLRP3 inflammasome, suppression of inflammation with Curcumin?

A Saeedi‐Boroujeni… - Basic & Clinical …, 2021 - Wiley Online Library
destructive role of inflammatory monocytes and macrophages indicate the role of inflammation
in COVID-19 … storm are the two main causes of severe COVID-19. Recently, Liao et al, …

Dysimmunity and inflammatory storm: watch out for bone lesions in COVID-19 infection

H Tao, G Ge, W Li, X Liang, H Wang, N Li, H Sun… - Medical …, 2020 - Elsevier
… We need to inform the patients about the possible bone destruction and joint inflammation
through the health education. Similarly, the mental health of the patient cannot be ignored. …

[HTML][HTML] Weathering the storm: harnessing the resolution of inflammation to limit COVID-19 pathogenesis

E Silberberg, JG Filep, A Ariel - Frontiers in Immunology, 2022 - frontiersin.org
… At this point, the looming cytokine storm breaks loose, forming a destructive feedforward
loop, in which the inflammatory reaction damages tissues, and the lungs in particular, which …

[HTML][HTML] Inflammation in COVID-19: from pathogenesis to treatment

RSY Wong - International journal of clinical and experimental …, 2021 - ncbi.nlm.nih.gov
inflammation in COVID-19. This review gives an overview of the role of inflammation in
COVID-19… that target the immune system and inflammation in COVID-19, as well as highlights the …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
inflammatory cytokine overproduction are addressed in this work. The virus-mediated
down-regulation of ACE2 causes a burst of inflammatory … and treat COVID-19 associated acute …

[HTML][HTML] Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
inflammatory component. The viral-independent phase has been explained by the inflammatory
… due to the epitope spreading caused by prolonged tissue destruction (20, 61). It remains …

Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
… responses during severe coronavirus infections, while … inflammatory reactions in possible
approaches for COVID-19inflammatory response may play protective or destructive

[HTML][HTML] Targeting innate immunity by blocking CD14: Novel approach to control inflammation and organ dysfunction in COVID-19 illness

TR Martin, MM Wurfel, I Zanoni, R Ulevitch - EBioMedicine, 2020 - thelancet.com
… The profound innate inflammatory response in the lungs produces a strongly oxidative and
pro-… activation, which allows the virus to persist without triggering destructive inflammation[ …

[HTML][HTML] Damage to the vascular endothelium as a leading mechanism of COVID-19 systemic pathology

OA Gomazkov - Biology Bulletin Reviews, 2021 - Springer
… a special clinical syndrome of a destructive, pro-inflammatory etiology with manifestations
of … The mechanism of the destructive role of the coronavirus seems to be significant against …