[HTML][HTML] High density DNA methylation array with single CpG site resolution

M Bibikova, B Barnes, C Tsan, V Ho, B Klotzle, JM Le… - Genomics, 2011 - Elsevier
… and input from DNA methylation experts. … of CpG methylation using bisulfite-converted
genomic DNA. We applied this technology to analyze DNA methylation in normal and tumor DNA

Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation

MD Robinson, C Stirzaker, AL Statham… - Genome …, 2010 - genome.cshlp.org
DNA methylation is an essential … the DNA methylation landscape is often deregulated. There
are now numerous technologies available to interrogate the DNA methylation status of CpG

Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons

D Beck, M Ben Maamar, MK Skinner - Epigenetics, 2022 - Taylor & Francis
… in DNA methylation methods involves CpG density. The current study was designed to
investigate the CpG density … and correlate this to various DNA methylation analysis data sets. The …

[HTML][HTML] Local CpG density affects the trajectory and variance of age-associated DNA methylation changes

J Higham, L Kerr, Q Zhang, RM Walker, SE Harris… - Genome Biology, 2022 - Springer
… We analyze longitudinal human DNA methylation trajectories at 345,895 CpGs from 600 …
epigenetic changes at individual CpGs. We show that changes in methylation with age occur at …

[HTML][HTML] DNA Methylation variability among individuals is related to CpGs cluster density and evolutionary signatures

D Palumbo, O Affinito, A Monticelli, S Cocozza - BMC genomics, 2018 - Springer
… We analyzed methylation variability values in relation to CpG cluster density and we found
a … Furthermore, we found that genes related to CpGs with high methylation variability values …

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl‐CpG binding protein.

J Boyes, A Bird - The EMBO journal, 1992 - embopress.org
CpG density of the genes used in this study. The transcribed regions of the three genes
are pictured below the title of each gene; the open boxes represent exons and the thin lines …

DNA methylation and gene expression

Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… their CpG density whereas methylated regions lose their CpG density due to mutations.
Indeed, … between methylation and CpG density; higher CpG density is associated with lower …

DNA methylation in human epigenomes depends on local topology of CpG sites

C Lövkvist, IB Dodd, K Sneppen… - Nucleic acids …, 2016 - academic.oup.com
CpG clusters on the basis of short distances between CpGs within … of methylation on the
number and density of CpG organization. CpG clusters with fewer, or less densely spaced, CpGs

Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

AM Cotton, EM Price, MJ Jones… - Human molecular …, 2015 - academic.oup.com
… We examined the interplay of DNA methylation (DNAm) with CpG density, transcriptional
activity and chromatin state at genes on the X chromosome using over 1800 female samples …

… of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG …

SS Nair, MW Coolen, C Stirzaker, JZ Song… - Epigenetics, 2011 - Taylor & Francis
CpG densities and DNA methylation density of the detected regions. The CpG densities for
… where a CpG density of 12 or greater represents a CpG island (Fig. 4A). We determined the …