DNA methylation status predicts cell type‐specific enhancer activity

M Wiench, S John, S Baek, TA Johnson… - The EMBO …, 2011 - embopress.org
… We observe a global enrichment of CpG density for pre‐… novo) are characterized by low CpG
density, and form a unique class … changes in methylation levels at selected CpGs within de …

Genomic patterns and context specific interpretation of DNA methylation

T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
… While the above mechanisms may account for the genome wide anti-correlation between
CpG density and DNA methylation, a subset of CpG rich promoters remains fully …

Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

I Taniguchi, C Iwaya, K Ohnaka, H Shibata… - Human genomics, 2017 - Springer
… However, it is known that DNA methylation status varies between cell … in DNA methylation
status between LCLs and PBCs is important in human population studies that use these DNA

DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation

MC Lorincz, D Schübeler, SR Hutchinson… - … and cellular biology, 2002 - Taylor & Francis
… the existence of a Dnmt3a/b-independent de novo MTase activity that is stimulated by
preexisting m CpGs, yielding a progressive increase in methylation density with time in culture. …

Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

MK Skinner, C Guerrero-Bosagna - Bmc Genomics, 2014 - Springer
… identification of DNA methylation at cytosines adjacent to guanine (CpG) … DNA methylation
analysis was biased to high density CpG regions that were subsequently referred to as CpG

Cell type–specific DNA methylation at intragenic CpG islands in the immune system

AM Deaton, S Webb, ARW Kerr, RS Illingworth… - Genome …, 2011 - genome.cshlp.org
… environment regardless of methylation state. Our results indicate that DNA methylation changes
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …

A practical guide to the measurement and analysis of DNA methylation

BD Singer - American journal of respiratory cell and molecular …, 2019 - atsjournals.org
… Integration with ChIP-seq can be performed by examining DNA methylation at well-observed
CpGs across putative enhancers identified by occupancy of histone 3 lysine 4 …

DNA methylation: old dog, new tricks?

CG Spruijt, M Vermeulen - Nature structural & molecular biology, 2014 - nature.com
… may be particularly relevant on enhancers or other DNA elements with a low CpG density.
On DNA stretches with a high CpG density, we expect that repressive MBDs will usually be the …

DNA methylation and CpG suppression

DN Cooper, S Gerber-Huber - Cell differentiation, 1985 - Elsevier
CpG may prove to be a useful indirect means to study the function of DNA methylation, it is of
interest that the observed 'CpG … for maintaining a relatively high CpG level in these regions …

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

K Day, LL Waite, A Thalacker-Mercer, A West… - Genome biology, 2013 - Springer
… tissue-specific DNA methylation changes with age that are reflective of CpG landscape and
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation. …