DNA methylation status predicts cell type‐specific enhancer activity
M Wiench, S John, S Baek, TA Johnson… - The EMBO …, 2011 - embopress.org
… We observe a global enrichment of CpG density for pre‐… novo) are characterized by low CpG
density, and form a unique class … changes in methylation levels at selected CpGs within de …
density, and form a unique class … changes in methylation levels at selected CpGs within de …
Genomic patterns and context specific interpretation of DNA methylation
T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
… While the above mechanisms may account for the genome wide anti-correlation between
CpG density and DNA methylation, a subset of CpG rich promoters remains fully …
CpG density and DNA methylation, a subset of CpG rich promoters remains fully …
Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines
I Taniguchi, C Iwaya, K Ohnaka, H Shibata… - Human genomics, 2017 - Springer
… However, it is known that DNA methylation status varies between cell … in DNA methylation
status between LCLs and PBCs is important in human population studies that use these DNA …
status between LCLs and PBCs is important in human population studies that use these DNA …
DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation
MC Lorincz, D Schübeler, SR Hutchinson… - … and cellular biology, 2002 - Taylor & Francis
… the existence of a Dnmt3a/b-independent de novo MTase activity that is stimulated by
preexisting m CpGs, yielding a progressive increase in methylation density with time in culture. …
preexisting m CpGs, yielding a progressive increase in methylation density with time in culture. …
Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions
MK Skinner, C Guerrero-Bosagna - Bmc Genomics, 2014 - Springer
… identification of DNA methylation at cytosines adjacent to guanine (CpG) … DNA methylation
analysis was biased to high density CpG regions that were subsequently referred to as CpG …
analysis was biased to high density CpG regions that were subsequently referred to as CpG …
Cell type–specific DNA methylation at intragenic CpG islands in the immune system
… environment regardless of methylation state. Our results indicate that DNA methylation changes
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
A practical guide to the measurement and analysis of DNA methylation
BD Singer - American journal of respiratory cell and molecular …, 2019 - atsjournals.org
… Integration with ChIP-seq can be performed by examining DNA methylation at well-observed
CpGs across putative enhancers identified by occupancy of histone 3 lysine 4 …
CpGs across putative enhancers identified by occupancy of histone 3 lysine 4 …
DNA methylation: old dog, new tricks?
CG Spruijt, M Vermeulen - Nature structural & molecular biology, 2014 - nature.com
… may be particularly relevant on enhancers or other DNA elements with a low CpG density.
On DNA stretches with a high CpG density, we expect that repressive MBDs will usually be the …
On DNA stretches with a high CpG density, we expect that repressive MBDs will usually be the …
DNA methylation and CpG suppression
DN Cooper, S Gerber-Huber - Cell differentiation, 1985 - Elsevier
… CpG may prove to be a useful indirect means to study the function of DNA methylation, it is of
interest that the observed 'CpG … for maintaining a relatively high CpG level in these regions …
interest that the observed 'CpG … for maintaining a relatively high CpG level in these regions …
Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
K Day, LL Waite, A Thalacker-Mercer, A West… - Genome biology, 2013 - Springer
… tissue-specific DNA methylation changes with age that are reflective of CpG landscape and
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation. …
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation. …