[HTML][HTML] The evolution of CpG density and lifespan in conserved primate and mammalian promoters
… pattern of DNA methylation degrades, with highly methylated CpG sites gradually becoming
… in CpG density that evolved over thousands of generations with changes in CpG methylation …
… in CpG density that evolved over thousands of generations with changes in CpG methylation …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… removing the methyl group from methylated CpG-containing DNA in cell free reactions as well
… CpG dinucleotides, suggesting that DNA methylation may contribute to these mutations.92 …
… CpG dinucleotides, suggesting that DNA methylation may contribute to these mutations.92 …
Genome-Wide Dna Methylation Profiling Using Infinium® Assay
M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
… We make an assumption that adjacent CpG sites tend to be co-methylated or co-… In summary,
we optimized the efficiency of the EZ DNA Methylation bisulfite conversion kit from Zymo …
we optimized the efficiency of the EZ DNA Methylation bisulfite conversion kit from Zymo …
DNA methylation and environmental exposures in human hepatocellular carcinoma
… of hypermethylation of CpG islands in tumor … methylation status of CpG islands in HCCs
from countries with various HCC risks. Methods: We examined the methylation status of 12 CpG …
from countries with various HCC risks. Methods: We examined the methylation status of 12 CpG …
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome
… Following the great acceptance of the human DNA methylation microarrays, … DNA methylation
microarray (Infinium Mouse Methylation BeadChip) that interrogates 280,754 unique CpG …
microarray (Infinium Mouse Methylation BeadChip) that interrogates 280,754 unique CpG …
[HTML][HTML] Multi-tissue DNA methylation age predictor in mouse
… Our model, which estimates age based on DNA methylation at 329 unique CpG sites, has a
… While females and males show no significant differences in predicted DNA methylation age, …
… While females and males show no significant differences in predicted DNA methylation age, …
DNA methylation and cancer
M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
… , CpG density itself does not influence gene expression. This regulation is dependent solely
on the DNA methylation … genes are characterized by methylation within promoter region (eg, …
on the DNA methylation … genes are characterized by methylation within promoter region (eg, …
[HTML][HTML] Genome-wide DNA methylation scan in major depressive disorder
… values from control sample DNA, while the black bars represent those from MMD samples.
The Y-axis is percent DNA methylation, while the X-axis shows each CpG arrayed along the …
The Y-axis is percent DNA methylation, while the X-axis shows each CpG arrayed along the …
A unique regulatory phase of DNA methylation in the early mammalian embryo
… in mammals is an epigenetic modification that is largely restricted to CpG dinucleotides and
… , CpG methylation exhibits global patterns based on relative CpG density: CpG islands at …
… , CpG methylation exhibits global patterns based on relative CpG density: CpG islands at …
[HTML][HTML] Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model
… sites play a significant role in adaptive evolution by reducing CpG density at TSS over time,
resulting in higher methylation levels in these regions and more permanent changes to lower …
resulting in higher methylation levels in these regions and more permanent changes to lower …