… In conclusion, we have developed MCA, a novel method to selectively amplify methylated
CpG islands. Using MCA coupled with RDA, 33 clones differentially methylated in colorectal …

… of promoter region CpG islands is associated … of CpG island methylation in colorectal
cancer, we have used a recently developed technique called methylated CpG island amplification …

… pllficatlons of a GCC repeat adjacent to a CpG Island in Xq28 of the human X chromosome.
… Individuals have >200 cop ies and alao have methylation at the CpG island. This sltuatlon is …

… (A) Methylation of multiple CpG islands detected by methylated CpG island amplification.
Methylated CpG island amplification products from colon adenomas (P2–P48) were blotted on …

… CpG islands without requiring prior knowledge of their DNA sequence, and 4) novel differentially
methylated CpG islands can be amplified … CpG sites within CpG islands, 3) CpG islands …

… In order to estimate the proportion of clones containing sequences derived from CpG
islands, we amplified inserts from the clones using primers which flanked the cloning site, and …

… method known as methylated CpG island amplification (MCA)… wide screening of aberrantly
methylated CpG-rich sequences. … hypermethylation of a CpG island showing promoter activity. …

… The results showed that in all three cases, sequences within the CpG islands were amplified
from nascent strands of small size that contained little or no sequences derived from the …

… So far, epigenomic studies have succeeded in identifying CpG islands, but recent evidence
points towards a role for transposable elements in epigenetic regulation, causing the fields of …

… Mammalian genomes are punctuated by DNA sequences containing an atypically high
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation and …