Epigenomics: beyond CpG islands

MJ Fazzari, JM Greally - Nature Reviews Genetics, 2004 - nature.com
… , originally defined as representing the hypomethylated fraction of the genome 7 and … We
look critically at CpG island biology in the context of the more detailed genome sequence that …

CpG islands

F Antequera, A Bird - DNA methylation: molecular biology and biological …, 1993 - Springer
… across particular regions could be analysed by genomic sequencing methods. The 5' CpG
island at the human phosphoglycerate kinase 1 gene is non-methylated at all 61 CpGs over a …

[HTML][HTML] CpG islands–'a rough guide'

RS Illingworth, AP Bird - FEBS letters, 2009 - Elsevier
genomes are punctuated by DNA sequences containing an atypically high frequency of CpG
sites termed CpG islands (… function in X-inactivation and genomic imprinting. More recently, …

[HTML][HTML] CpG island mapping by epigenome prediction

C Bock, J Walter, M Paulsen… - PLoS computational …, 2007 - journals.plos.org
… of all CpG islands in the human genome, giving rise to an improved and more accurate …
combine an initial, sequence-based mapping of CpG islands with subsequent prediction of …

[HTML][HTML] CpGcluster: a distance-based algorithm for CpG-island detection

M Hackenberg, C Previti, PL Luque-Escamilla… - BMC …, 2006 - Springer
… (CpG islands or CGIs), totaling 1% of the genome, where … The DNA chromosome
sequence is scanned for CpG … ... x N , N being the total number of CpGs in the sequence. The …

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

D Takai, PA Jones - Proceedings of the national academy of …, 2002 - National Acad Sciences
… We have therefore used the complete genomic sequences of human chromosomes 21 and
22 to examine the properties of CpG islands in different sequence classes by using a search …

Gene‐associated CpG islands in plants as revealed by analyses of genomic sequences

I Ashikawa - The Plant Journal, 2001 - Wiley Online Library
… Therefore, we consider that a CpG frequency profile across genomic sequences that …
identifying plant CpG islands than traditional methods do. Plant genomes contain CpG islands more …

… chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an …

GP Pfeifer, SD Steigerwald… - Proceedings of the …, 1990 - National Acad Sciences
… This method provides high-quality sequence ladders suitable … genomic sequencing to
determine cytosine methylation in both strands of 62 CpG sites (information obtained for 121 CpG

[HTML][HTML] CpG island density and its correlations with genomic features in mammalian genomes

L Han, B Su, WH Li, Z Zhao - Genome biology, 2008 - Springer
… of CpG islands in ten mammalian genomes. We found that both the number of CpG islands
and their density vary greatly among genomes… Because of incomplete genome sequence and …

CpG islands in vertebrate genomes

M Gardiner-Garden, M Frommer - Journal of molecular biology, 1987 - Elsevier
… Where no CpG island was present in the sequence (Table l), we have included a … C and
Obs/Exp CpG for the total sequence. Where a CpG island was present in the sequence (Table 2)…