CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
M Esteller - Oncogene, 2002 - nature.com
… Hypermethylation of CpG islands located in the promoter … CpG island hypermethylation
has been described in almost … Hypermethylation is not an isolated layer of epigenetic control, …
has been described in almost … Hypermethylation is not an isolated layer of epigenetic control, …
Molecular biomarker in prostate cancer: the role of CpG island hypermethylation
PJ Bastian, S Yegnasubramanian, GS Palapattu… - European urology, 2004 - Elsevier
… CpG island hypermethylation patterns in other urological malignancies.Using modern analytic
methods, CpG island hypermethylation … potential use of CpG island hypermethylation as a …
methods, CpG island hypermethylation … potential use of CpG island hypermethylation as a …
Analysis of promoter CpG island hypermethylation in cancer: location, location, location!
IJH Van Vlodrop, HEC Niessen, S Derks… - Clinical cancer …, 2011 - AACR
… functional link between PcG protein binding and CpG island hypermethylation. First, the
reported percentage of PcG-binding sites that correspond to CpG islands ranges from 50% to 88…
reported percentage of PcG-binding sites that correspond to CpG islands ranges from 50% to 88…
Genomic insights into cancer-associated aberrant CpG island hypermethylation
… of DNA methylation levels and the aberrant hypermethylation of some sequences, particularly
CpG islands (CGIs). This aberrant hypermethylation is often invoked as a mechanism …
CpG islands (CGIs). This aberrant hypermethylation is often invoked as a mechanism …
CpG island hypermethylation of tumor suppressor microRNAs in human cancer
A Lujambio - Cell cycle, 2007 - Taylor & Francis
… silencing associated with CpG island hypermethylation.After … We have demonstrated that
CpG island hypermethylation is … is associated with a CpG island. After bisulphite sequencing …
CpG island hypermethylation is … is associated with a CpG island. After bisulphite sequencing …
GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer
M Nakayama, ML Gonzalgo… - Journal of cellular …, 2004 - Wiley Online Library
… In this review, the potential utility of somatic GSTP1 CpG island hypermethylation change as
a molecular biomarker for prostate cancer screening, detection, and diagnosis, is considered…
a molecular biomarker for prostate cancer screening, detection, and diagnosis, is considered…
CpG island hypermethylation in human astrocytomas
… hypermethylated CpG islands … of hypermethylated CpG islands. These clusters were defined
as a minimum of five adjacent CpG islands that underwent simultaneous hypermethylation …
as a minimum of five adjacent CpG islands that underwent simultaneous hypermethylation …
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
S Lee, HJ Lee, JH Kim, HS Lee, JJ Jang… - The American journal of …, 2003 - Elsevier
… The down-regulation of E-cadherin is related to allelic deletion of the gene or CpG island
hypermethylation of the promoter CpG islands and both mechanisms have been demonstrated …
hypermethylation of the promoter CpG islands and both mechanisms have been demonstrated …
Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies
DJ Smiraglia, LJ Rush, MC Frühwald… - Human molecular …, 2001 - academic.oup.com
… snapshot’ of the CpG island hypermethylation phenotype in the genomes of primary
malignancies and cell lines by assessing the methylation state of 1184 CpG islands in each sample. …
malignancies and cell lines by assessing the methylation state of 1184 CpG islands in each sample. …
The role of H3K4 trimethylation in CpG islands hypermethylation in cancer
G Zardo - Biomolecules, 2021 - mdpi.com
… cells, and the mode of promoter CpG island hypermethylation in cancer. They observed that
… DNA hypermethylated islands and is notably absent from the internal borders of the islands …
… DNA hypermethylated islands and is notably absent from the internal borders of the islands …