… of the released chromatin. Taken to- gether, these results imply that CpG island chromatin
is … Hl is present yet bound more weakly to this chromatin so that 450 mM NH&I is sufficient to …

… binding without significantly reducing CpG density destroy the immunity of a CpG island to
DNA methylation 25,26 . It follows that H3K4 methylation due to CpG clustering may not be …

… termed CpG islands because … CpG islands, which remain protected from methylation in
normal cells, are susceptible to methylation in tumor cells. How the CpG moieties in CpG islands …

… is the default chromatin structure for CpG-rich, G + C-rich DNA. A high CpG density alone is
… de novo DNA methylation leading to loss of CGI signature chromatin. We conclude that both …

… CpG islands may have a role in chromatin organiza tion during spermatogenesis CpG
islands may also be necessary for chromatin … Extensive changes in chromatin structure occur …

… Citation27,Citation42–Citation44,Citation46 One explanation for this relationship is that
chromatin structure at CpG islands creates an accessible environment that favors binding of …

… can be accurately predicted from the CpG dinucleotide frequency. Within the collected
database of human CpG island gene sequences, the over-abundance of (CpG) 3 is even more …

… may drive them into an Mspl-insensitive chromatin structure. To test this in other CpG islands,
we analyzed chromatin at 10 of the random island sequences used previously (see Figure …

… bivalent chromatin domains precisely span the CpG island clusters. We conclude that CpG
island structure plays a fundamental role in defining TrxG/PcG chromatin structure in human …

… CpG islands (CGIs) are short interspersed DNA sequences that deviate significantly from the
average genomic pattern by being GC-rich, CpG-… to influence local chromatin structure and …