DNA methylation: TET proteins—guardians of CpG islands?
K Williams, J Christensen, K Helin - EMBO reports, 2012 - embopress.org
… adjusting methylation levels, and it is largely unknown what prevents the accumulation of
DNA methylation at CpG islands. Importantly, despite an intense search, no direct DNA …
DNA methylation at CpG islands. Importantly, despite an intense search, no direct DNA …
CpG islands
F Antequera, A Bird - DNA methylation: molecular biology and biological …, 1993 - Springer
… Consistent failure to methylate any region of DNA in the germline would automatically lead
to CpG island-like properties at that sequence, since CpGs would not be methylated and …
to CpG island-like properties at that sequence, since CpGs would not be methylated and …
DNA methylation and chromatin structure: the puzzling CpG islands
P Caiafa, M Zampieri - Journal of cellular biochemistry, 2005 - Wiley Online Library
… that these regions are termed CpG islands because they are … for enzymes involved in DNA
methylation. Anomalous insertion of … CpG islands, which remain protected from methylation in …
methylation. Anomalous insertion of … CpG islands, which remain protected from methylation in …
DNA methylation profiles of CpG islands for cellular differentiation and development in mammals
K Shiota - Cytogenetic and genome research, 2004 - karger.com
… methylated regions (T-DMR), which are potential methylation … -DMRs in CpG islands revealed
that the DNA methylation profile … Differentiation of cells is associated with both methylation …
that the DNA methylation profile … Differentiation of cells is associated with both methylation …
[HTML][HTML] DNA motifs associated with aberrant CpG island methylation
… DNA pattern recognition and supervised learning techniques, we found that methylation-prone
and methylation-resistant CpG islands could … of CpG islands to aberrant DNA methylation. …
and methylation-resistant CpG islands could … of CpG islands to aberrant DNA methylation. …
Predicting aberrant CpG island methylation
… , we identified a subset of methylation-prone CpG islands (3.8%) … Methylation-prone and
methylation-resistant CpG islands … DNA methylation in mammals occurs at cytosines residues …
methylation-resistant CpG islands … DNA methylation in mammals occurs at cytosines residues …
The DNA methylation paradox
PA Jones - Trends in genetics, 1999 - cell.com
… Not all CpG islands and methylation sites are located in … methylation paradox might be
resolved if it is hypothesized that transcription through a CpG island facilitates de novo methylation…
resolved if it is hypothesized that transcription through a CpG island facilitates de novo methylation…
[HTML][HTML] CpG islands–'a rough guide'
RS Illingworth, AP Bird - FEBS letters, 2009 - Elsevier
… Mammalian genomes are punctuated by DNA sequences containing an atypically high
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation and …
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation and …
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
… , highly significant CpG island–dependent correlations between age and methylation; loci
in CpG islands gained methylation with age, loci not in CpG islands lost methylation with age (…
in CpG islands gained methylation with age, loci not in CpG islands lost methylation with age (…
Cell type–specific DNA methylation at intragenic CpG islands in the immune system
… environment regardless of methylation state. Our results indicate that DNA methylation changes
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
play … The dinucleotide sequence CpG is the predominant site of DNA methylation in the …
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