Genome-wide analysis of DNA methylation status of CpG islands in embryoid bodies, teratomas, and fetuses
… of embryonic stem (ES) cells into embryoid bodies (EBs) … We have previously reported that
there are 247 CpG islands … of DNA methylation patterns at CpG islands is a crucial epigenetic …
there are 247 CpG islands … of DNA methylation patterns at CpG islands is a crucial epigenetic …
Dimethyl sulfoxide has an impact on epigenetic profile in mouse embryoid body
… are located in CpG islands [44]. We have identified many regions in CpG islands that have
… However, note that there are approximately 15,500 CpG islands in the mouse genome [46], …
… However, note that there are approximately 15,500 CpG islands in the mouse genome [46], …
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
SA Smallwood, S Tomizawa, F Krueger, N Ruf… - Nature …, 2011 - nature.com
… Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is
essential to understand genomic imprinting and epigenetic reprogramming 1,2,3 . Here we …
essential to understand genomic imprinting and epigenetic reprogramming 1,2,3 . Here we …
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
… mESCs to embryoid body formation assays. RT–qPCR analyses of 4-day embryoid bodies
demonstrated that although all lineage genes are upregulated after embryoid body induction, …
demonstrated that although all lineage genes are upregulated after embryoid body induction, …
Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
… at CpG island 'shores', regions of comparatively low CpG density that are located near
traditional CpG islands, than at the CpG islands … of ∼4.6 million CpG sites genome-wide using a …
traditional CpG islands, than at the CpG islands … of ∼4.6 million CpG sites genome-wide using a …
Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes
SM Lee, J Lee, KM Noh, WY Choi… - Proceedings of the …, 2017 - National Acad Sciences
… Approximately 70% of the total CpG, 5′-C-phosphate-G-3′, sites in the mammalian
genome are methylated, but CpG sites in crowded contexts, such as CpG islands (CGIs), are …
genome are methylated, but CpG sites in crowded contexts, such as CpG islands (CGIs), are …
Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal
… decisions as assessed in teratomas and embryoid bodies, indicating that Pcl3 has a specific
… many of the same PRC2 targets, particularly CpG islands regulated by Pcl3. Thus, Pcl3 is a …
… many of the same PRC2 targets, particularly CpG islands regulated by Pcl3. Thus, Pcl3 is a …
DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease
DM Jeziorska, RJS Murray… - Proceedings of the …, 2017 - National Acad Sciences
… signatures similar to those observed in the EBV-ZF and MELxZF cell lines, we established
chromatin profiles in ZFαAS and ZFαS mES cells and in in vitro-differentiated embryoid bodies …
chromatin profiles in ZFαAS and ZFαS mES cells and in in vitro-differentiated embryoid bodies …
[PDF][PDF] Investigating the role of DNA methylation in pluripotency and differentiation using an embryoid body model
P Jackson - 2023 - core.ac.uk
… I allow these cells to differentiate to form embryoid bodies (EBs), a validated embryogenesis-like
model that enables simulation of the pluripotent-to-differentiated transition in vitro. By …
model that enables simulation of the pluripotent-to-differentiated transition in vitro. By …
Developmental programming of CpG island methylation profiles in the human genome
R Straussman, D Nejman, D Roberts… - Nature structural & …, 2009 - nature.com
… To compile a complete data set of CpG island methylation in the human genome, we … CpG
island list and contains 237,000 probes covering more than 90% of the 27,639 CpG islands at …
island list and contains 237,000 probes covering more than 90% of the 27,639 CpG islands at …
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