… A second approach to regenerating hair cells would be to find genes essential for … critical
genes for embryonic hair cell formation such as the cell cycle related proteins, the Atoh1 gene …

… Although most of the identified genes are possible novel candidates involved in hair cell
development, we found some that have previously been associated with hair‐bundle …

… We show the presence of distinct critical periods for Atoh1 in each of these … hair cell function.
Finally, we show that the supporting cell death that accompanies loss of Atoh1 in hair cells …

… These hair cell regeneration genes fell into distinct and … , we found these hair cell regeneration
genes often also affected … Genetic factors play a critical role in each of these processes. …

… different types of stereociliary links critical for hair-bundle cohesion and … genetics with
modern molecular and cell biology tools will continue to shed light on unresolved questions in hair-…

… Bowcock for her critical reading of this manuscript. We are particularly grateful for financial
support from the National Organization for Hearing Research Foundation and from the NIDCD …

… suggest that Rb is critical for maintenance of the postmitotic state of hair cells.In addition to
… of hair cells, Rb is also critical for the survival of postnatal hair cells because hair cell death …

… four rows of hair cells are … cells formerly prohibited from differentiating into hair cells can
now do so. Thus, the Notch pathway does appear to play a critical role in limiting the hair cell …

… To our knowledge, Math1 is the first gene shown to be required for the specification of hair
cells. We propose thatMath1 acts as a “pro–hair cell gene” in the developing sensory epithelia…

… analysis for the following reasons: First, our analyses were based on two separate types of
hair cells and thus provide critical information of what genes are uniquely expressed in each …