Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule

MA Gates‐Hollingsworth, TR Kozel - Molecular microbiology, 2009 - Wiley Online Library
capsular matrix surrounding each cell is a complex process that is still poorly understood.
The goal of our study was to examine expression of capsular epitopesexpression of epitopes

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
… Although capsules are commonly found among bacteria, there are a few encapsulated …
The best characterized fungal capsule belongs to Cryptococcus neoformans. The capsule of this …

Immunoregulation by capsular components of Cryptococcus neoformans

A Vecchiarelli - Medical mycology, 2000 - academic.oup.com
Cryptococcus neoformans glycoprotein produced as an exoantigen bearing a glycosylated
species-specifi c epitope… oxide synthase expression, and altered antibody responsiveness to …

The capsular dynamics of Cryptococcus neoformans

D McFadden, O Zaragoza, A Casadevall - TRENDS in Microbiology, 2006 - cell.com
… to acetylate GXM fully in the absence of CAS31 expression [ … Factor 1 defines an antigenic
determinant present in all strains and probably represents a complex group of epitopes [ …

Antibody Interactions with the Capsule ofCryptococcus neoformans

M Feldmesser, J Rivera, Y Kress, TR Kozel… - Infection and …, 2000 - Am Soc Microbiol
Cryptococcus neoformans produce different immunofluorescence (IF) patterns after binding
to the polysaccharide capsule… that the epitope recognized by this MAb is not expressed by C. …

… epitope exhibits serotype-specific accessibility and redistributes towards the capsule surface during titanization of the fungal pathogen Cryptococcus neoformans

M Probert, X Zhou, M Goodall, SA Johnston… - Infection and …, 2019 - Am Soc Microbiol
… to its expression by titan cells. Intriguingly, we noticed that the spatial distribution of this
epitope differs within the capsules produced by the three C. neoformans morphotypes found …

Capsule Structural Heterogeneity and Antigenic Variation in Cryptococcus neoformans

DC McFadden, BC Fries, F Wang, A Casadevall - Eukaryotic Cell, 2007 - Am Soc Microbiol
… the capsular polysaccharide of C. neoformans, we examined the expression of PS epitopes
in … suggest that the epitope for MAb 21D2 is variably expressed in the capsule of the serotype …

Radial Mass Density, Charge, and Epitope Distribution in the Cryptococcus neoformans Capsule

ME Maxson, E Dadachova, A Casadevall… - Eukaryotic …, 2007 - Am Soc Microbiol
… of Cryptococcus neoformans cells to gamma radiation results in a gradual release of capsular
… This method allows the systematic exploration of different capsular regions. Using this …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
… secretion and attachment of capsule under low-iron conditions instead of the expression of
… results in the production of specific antibodies to various capsule epitopes. Most individuals …

Contribution of Epitope Specificity to the Binding of Monoclonal Antibodies to the Capsule of Cryptococcus neoformans and the Soluble Form of Its Major …

RM Duro, D Netski, P Thorkildson… - Clinical and Vaccine …, 2003 - Am Soc Microbiol
… Our results raise the possibility that epitope expression by shed (soluble) GXM is different
than epitope expression by capsular GXM. Such a disconnect is suggested by a comparison of …