… In this review, we describe iron uptake and regulatory mechanisms in C. neoformans, in …
This group also demonstrated that copper regulates ferric reductase activity and identified …

… neoformans acquires iron by multiple mechanisms, including a ferroxidase-… ferric reductase
genes and their contributions to iron acquisition as well as to ferric and cupric reductase …

… a similar ferric reductase in C. neoformans. Both organisms exhibit similar maximal ferric
reductase activities when depleted of iron—57 and 20 nmol of Fe(III) per 106 cells per h by …

… , we examined the ferric reductase and cupric reductase activities of mutant strainfrr1 606 .
… regulation of ferric reductase or cupric reductase by copper in the presence of iron (Table 3)…

… We found approximately 80% inhibition of the cryptococcal ferric reductase by 4 μM Pt(II);
when we performed uptake experiments with 5.6 μM Pt(II), deferoxamine-stimulated uptake …

… Ferric reductases believed to reduce iron at the cell surface also support subsequent iron …
uptake system consisting of ferric reductases (eg Fre2 and Fre4), the iron permease Cft1 and …

… of iron regulation and acquisition in the fungal pathogen Cryptococcus neoformans, and here…
by cell surface reductases, followed by ferrous iron oxidation by a ferroxidase coupled to an …

… Second, a regulated high-affinity ferric reductase operates in low iron conditions, such as
those present in a mammalian host. The produced Fe 2+ is further oxidized to Fe 3+ by a …

… ferric reductase was found to be regulated by Zn ÷+ [7]. A cytoplasmic ferric reductase
purified from Rhodopseudomonas sphaeroides reduced ferric tris and ferric citrate but not ferric …

… One is a reductive pathway in which ferric iron is reduced to ferrous iron by cell surface
reductase activity with subsequent transport across the plasma membrane by the high-affinity …