… neoformans also produces a wide range of phenotypes within the host. Some of these
phenotypic … in pleomorphic cells, and hypervirulence when compared to H99 derivatives without …

… These phenotypes were mirrored by a virulence defect in the vps23 mutant in a mouse model
of cryptococcosis and by hypervirulence of the overexpression strain. Overall, these results …

… , Cryptococcus neoformans, has been shown to undergo replicative aging. Old cells are
characterized by advanced generational age and phenotypic … not lead to hypervirulence is most …

… was known to be associated with patient CSF fungal burdens and the hypervirulent C.
gattii strains that exhibited enhanced intracellular proliferation rate was correlated with mouse …

… In addition, the incidence of non-HIV-associated CM is increasing in Pacific north-western
America and far east Asia, caused by hypervirulent strains of Cryptococcus gattii and …

… phenotypic display against external factors. This review examines several transcription
factors germane to Cryptococcus (C.) neoformans … to adaptive phenotypes and morphological …

… hypervirulence of nth2Δ strains. … hypervirulence phenotype, indicating that NTH1 was not
compensating for the loss of NTH2 activity. Furthermore, there was no change in the phenotype …

… mating and virulence of Cryptococcus neoformans var. grubii (… hypervirulent. Because
other mutations have been observed to confer different phenotypes in two diverged varieties of C…

… in mice, leading to severe symptoms of cryptococcosis, early mortality and higher fungal …
the hypervirulent and cross-resistant phenotype, suggesting a persistent effect of BEN on C. …

… Background: Cryptococcus neoformans is an opportunistic fungal pathogen that can cause
… The objective of this work was to study the relationship between the phenotypes and …