… Using a large collection of ClinCn isolates, we uncovered highly variable phenotypes of C. …
in contrast with what was demonstrated for the clonal hypervirulent VGII C. gattii isolates (13). …

… , we characterized a range of survival phenotypes for these strains when exposed to host
cells of different species. We then performed serial passages of an environmentally isolated …

… Cryptococcus neoformans is an important basidiomycete … model pathogenic yeast
Cryptococcus neoformans, we generated … UBP5 generated many intriguing phenotypic changes in …

… gattii causes disease and to characterize hypervirulent C. gattii strains, we summarize the
… neoformans strain ATCC 24066 phenotype is accompanied by decreased expression of …

… In contrast, loss of PKR1 causes an enlarged capsule and hypervirulence [28]. The
underlying mechanisms for these intriguing phenotypes are clearly important for understanding …

… , and a mutant defective in O-acetylation was found to be hypervirulent [62, 63]. … Additionally,
C. neoformans exhibits phenotypic switching that influences the expression of virulence …

… capsule-defective strains, the rim101Δ mutant is hypervirulent in animal models of cryptococcosis.
… Using a combination of bioinformatic and phenotypic screening, we identified the C. …

Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS. …

… instance is the phenotypic differences observed between the series of strains derived from
the type strain of the human pathogenic fungus Cryptococcus neoformans. A second case …

… HPC, the Cryptococcus neoformans species complex (CNSC) and the Cryptococcus gattii
species … We investigated the effects of parental phenotypic variations on progeny phenotypic …