Role of ferric reductases in iron acquisition and virulence in the fungal pathogen Cryptococcus neoformans

S Saikia, D Oliveira, G Hu, J Kronstad - Infection and immunity, 2014 - Am Soc Microbiol
… in high-affinity iron uptake (eg, the cfo1 mutant). Overall, this study provides a more detailed
… of the iron acquisition components required for C. neoformans to cause cryptococcosis. …

The Mannoprotein Cig1 Supports Iron Acquisition From Heme and Virulence in the Pathogenic Fungus Cryptococcus neoformans

…, T Lian, G Hu, J Wang, C Biondo… - The Journal of …, 2013 - academic.oup.com
Iron acquisition is critical for virulence of the human pathogenic fungus Cryptococcus
neoformans. The cryptococcal transcript for the extracellular mannoprotein Cig1 is highly regulated …

Iron acquisition in the human fungal pathogen Cryptococcus neoformans

WH Jung, E Do - Current opinion in microbiology, 2013 - Elsevier
… of the pathogen influences its iron acquisition strategy. Herein, we review current findings
on the components and regulatory elements of the iron acquisition systems in C. neoformans. …

Cryptococcus neoformans requires the ESCRT protein Vps23 for iron acquisition from heme, for capsule formation, and for virulence

G Hu, M Caza, B Cadieux, V Chan, V Liu… - Infection and …, 2013 - Am Soc Microbiol
neoformans. Overall, this study extends our understanding of iron acquisition in C.
neoformans, reveals an additional complexity to the connection between …

Iron acquisition in fungal pathogens of humans

G Bairwa, W Hee Jung, JW Kronstad - Metallomics, 2017 - academic.oup.com
… , Cryptococcus neoformans and Aspergillus fumigatus. In particular, exciting new work illustrates
the importance of iron acquisition … also expanding our knowledge of iron uptake in less-…

Iron and fungal pathogenesis: a case study with Cryptococcus neoformans

WH Jung, JW Kronstad - Cellular microbiology, 2008 - Wiley Online Library
… is to develop mechanistic views of the iron acquisition functions and regulatory schemes that
operate when C. … In this review, we describe iron uptake and regulatory mechanisms in C. …

Iron acquisition by Cryptococcus neoformans

SE Vartivarian, RE Cowart, EJ Anaissie… - Journal of medical …, 1995 - academic.oup.com
iron reductase is operative in this organism, and if an iron(n) binding site exists on the surface
of the cell. In this report, we use the terms 'iron acquisition' and 'iron … or ferrous iron which is …

[HTML][HTML] Iron source preference and regulation of iron uptake in Cryptococcus neoformans

WH Jung, A Sham, T Lian, A Singh, DJ Kosman… - PLoS …, 2008 - journals.plos.org
… Overall, our results provide insights into the role of iron acquisition functions in cryptococcal
disease, reveal iron source preferences, and suggest possible targets for antifungal therapy, …

Role of Ferroxidases in Iron Uptake and Virulence of Cryptococcus neoformans

WH Jung, G Hu, W Kuo, JW Kronstad - Eukaryotic Cell, 2009 - Am Soc Microbiol
… of iron regulation and acquisition in the fungal pathogen Cryptococcus neoformans, and here…
We have investigated the iron acquisition systems and iron-related regulatory mechanisms …

Connecting iron regulation and mitochondrial function in Cryptococcus neoformans

LC Horianopoulos, JW Kronstad - Current opinion in microbiology, 2019 - Elsevier
Iron acquisition is essential for the proliferation of microorganisms, and human pathogens …
In this review, we summarize aspects of iron acquisition in C. neoformans to set the stage for a …