… strategies and mechanisms to optimally regulate iron acquisition, transport, storage, and …
human pathogens (Aspergillus fumigatus, Cryptococcus neoformans, and Candida albicans). …

… model for neisserial iron acquisition from transferrin proposes that Tbp2 preferentially binds
iron-charged transferrin passing it on to the Tbpl dimer, at which point the transferrin iron is …

… the fine line between essential metal acquisition and defense against their toxicity [1,3]. In
the environmental yeast, Cryptococcus neoformans, iron and copper regulate the expression …

… Candida albicans and Cryptococcus neoformans. We also discuss the extent to which the
newly identified functions add depth to our understanding of iron acquisition by fungi and …

… Some fungi have evolved a process of iron acquisition involving the synthesis of iron-gathering …
The CaFTR 1 gene was required for iron acquisition by C. albicans in iron-deficient …

… IMPORTANCE Cryptococcus neoformans and Cryptococcus gattii cause fatal infection in …
consideration is that almost all published Cryptococcus iron acquisition studies utilize C. …

… of targeted mutations in iron reductases and siderophore transporters, the Kronstad laboratory
has demonstrated the importance of iron acquisition in infection. Also the low-iron signal, …

… anthracis 7 and Cig1 of Cryptococcus neoformans 8 . … -iron acquisition pathway by the
fungal CFEM proteins. The novel CFEM helical-basket fold carries unique haem-binding and iron-…

… Cfo1 and Cir1 are involved in iron homeostasis and virulence in C. neoformans and they
were identified in this study in C. gattii. Many proteins related to iron in C. …

… for the ability of the fungal pathogen Cryptococcus neoformans to cause disease. However,
… or HapX, two transcription factors that regulate iron acquisition and use. In this regard, loss of …