… Iron assimilation studies in strain 564 were performed in asparagine salts containing 1 g …
Iron assimilation studies in strain B-3501 were performed in LIM (low iron medium) containing (1…

… cerevisiae can utilize siderophore-bound iron either by the reductive iron-assimilation system
or by membrane transporters. In the latter case, the uptake is mediated by four transporters …

… Finally, we note that exported reductants related to iron assimilation are potentially
deployed to intercept and neutralize incoming oxidants secreted by immunologic cells. …

… in iron availability to cause disease. Recent studies reveal that the pathogenic fungus
Cryptococcus neoformans overcomes iron … The regulation of iron uptake is mediated by an …

… Specificity for Fe(II) of the iron uptake step. Iron assimilation (iron-dependent growth) in C.
neoformansappears to require the reduction of Fe(III) to Fe(II) as a first step (13, 22, 27). We …

… iron from either haemoglobin or haem and can use iron from opsonized red blood cells. A
reductive iron assimilation … preliminary study on the assimilation of iron during the growth of C. …

… acquisition is critical for the ability of the pathogenic yeast Cryptococcus neoformans to …
view of the iron acquisition components required for C. neoformans to cause cryptococcosis. …

… mechanisms of iron regulation and acquisition in the fungal pathogen Cryptococcus neoformans,
and … Cfo1 is required for the reductive iron uptake system that mediates the utilization of …

… from host proteins, while others appear to require a membrane-bound iron … Cryptococcus
neoformans to use host iron sources including transferrin and heme, and we identify an iron …

… The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of …
indicate that iron is not readily available to C. neoformans in the host and that specific iron …