… in the host is extremely low but pathogens can obtain iron with high-affinity chelators (…
In this review, we describe iron uptake and regulatory mechanisms in C. neoformans, in …

… Cryptococcus neoformans must reduce Fe(III) to Fe(II) prior to uptake. We investigated
mechanisms of reduction using the chromogenic ferrous chelator … ferrous iron chelator and to …

… uptake by microbes which lack receptors for the iron chelate; … relieves iron starvation
caused by the avid synthetic chelator … experimental cryptococcosis in the guinea pig (1). Thus,…

… We studied the effects of iron chelators and of a thallium sait on growth of Cryptococcus
neofor… An oxidant-sensitive mutant strain was found to require exogenous ferric iron for growth. …

… iron chelating agents (siderophores) to mobilize iron from ferric ligands. The pathogenic yeast,
Cryptococcus neoformans has not … and its mechanism of iron acquisition is unknown. This …

… Cryptococcus neoformans and Candida albicans because these fungi employ high-affinity
iron permeases to acquire iron … -weight iron chelators that specifically bind ferric iron with high …

… Some fungi produce iron-chelating siderophores to capture iron from host … Cryptococcus
neoformans to use host iron sources including transferrin and heme, and we identify an iron …

… Extracellular free iron is chelated by transferrin, and free heme from the lysis of erythrocytes
… the solubility of iron itself, and different iron uptake systems in C. neoformans may be utilized …

… combinations, and EDTA, DSX and DFP antagonised the activity of azole drugs in strains of
Cryptococcus neoformans var. grubii. This study highlights the range of interactions that can …

… Cryptococcus neoformans and Cryptococcus gattii were used to determine the minimal
inhibitory concentrations (MICs) of DFO and DSX, and the fractional inhibitory concentration …