… -binding molecules (siderophores) and for high-affinity iron … to low-iron conditions and the
use of host iron sources such as … to repress iron-dependent functions during iron deprivation, …

… than wild-type cells in low-iron medium, and shows delayed growth and altered capsule
regulation in iron-replete medium. Iron deprivation also resulted in elevated SAGE tags for …

… For example, glucose scarcity is one of the challenges that the fungus must overcome during
infection [5, 6, 7], and recent studies revealed that iron deprivation may trigger a metabolic …

… Cryptococcus neoformans to use host iron sources including transferrin and heme, and we
identify an iron … neoformans responds to iron deprivation by increasing transcription of these …

… mechanisms of iron regulation and acquisition in the fungal pathogen Cryptococcus
neoformans, … The influence of iron deprivation on heme biosynthesis may also be involved in the …

… component of the cellular response to iron deprivation [57,58]. Although additional levels
of iron regulation have not yet been identified in Cr. neoformans, we hypothesize that the …

… ) and an iron permease (Cft1) is critical for the pathogenesis of Cryptococcus neoformans.
In … are negatively impacted by iron deprivation because these processes depend on specific …

… Iron acquisition is essential for the proliferation of microorganisms, and human pathogens …
Cryptococcus neoformans must use sophisticated uptake mechanisms to overcome host iron …

… Previous studies have implicated ferric reduction in the iron uptake pathway of the opportunistic
pathogen Cryptococcus neoformans. Here we studied iron uptake directly, using 55 Fe …

… neoformans has been considered an excellent model fungal pathogen to study iron … For
example, iron deprivation influences the formation of the polysaccharide capsule and synthesis …