… neoformans has been considered an excellent model fungal pathogen to study iron … For
example, iron deprivation influences the formation of the polysaccharide capsule and synthesis …

… acquisition is critical for the ability of the pathogenic yeast Cryptococcus neoformans to …
view of the iron acquisition components required for C. neoformans to cause cryptococcosis. …

… Iron availability is a key regulator of virulence factor elaboration in Cryptococcus neoformans…
In this yeast, iron deprivation results in sorting of the proteins back to the plasma membrane …

… cerevisiae include transcriptional activation by the proteins Aft1 and Aft2 in response to iron
deprivation, the participation of chromatin remodelling proteins, and the influence of iron on …

… The Cryptococcus neoformans species complex comprises basidiomycetous yeasts that
cause life-threatening diseases in humans and animals. There are two main pathogenic …

… availability on Cir1 and found that the abundance of the protein decreases upon iron
deprivation. This destabilization was influenced by reducing conditions and by inhibition of …

… was unaffected by iron nitriloacetate, demonstrating that chloroquine worked by a mechanism
independent of iron deprivation. There was an inverse correlation between growth of C. …

… We confirmed that Grx4 binds Cir1 and demonstrated that iron repletion promotes … iron-related
phenotypes similar to those of a cir1Δ mutant, including poor growth upon iron deprivation…

… Our study demonstrated that the transcript levels of the gene were decreased upon iron
deprivation. Similar down-regulation of LEU1 in iron-deprived conditions was previously …

… The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of …
indicate that iron is not readily available to C. neoformans in the host and that specific iron …