Coordinated regulation of iron metabolism in Cryptococcus neoformans by GATA and CCAAT transcription factors: connections with virulence
WH Jung, E Sánchez-León, JW Kronstad - Current genetics, 2021 - Springer
… that governing iron transport upon iron deprivation is a key role of the protein in C. … role
in regulating the response to iron deprivation compared to iron sufficiency. The ChIP-Seq and …
in regulating the response to iron deprivation compared to iron sufficiency. The ChIP-Seq and …
A Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for Capsule Formation in Cryptococcus neoformans
… human fungal pathogen Cryptococcus neoformans within the vertebrate host, and iron
sensing … In addition, upon iron deprivation, the CBC represses the expression of the GATA-type …
sensing … In addition, upon iron deprivation, the CBC represses the expression of the GATA-type …
Metals and the cell surface of Cryptococcus neoformans
P Xue, G Hu, WH Jung, JW Kronstad - Current Opinion in Microbiology, 2023 - Elsevier
… host immune response and influencing phagocytosis, and capsule elaboration is regulated
by a number of host-related conditions including iron deprivation 7, 8. Effective therapy for …
by a number of host-related conditions including iron deprivation 7, 8. Effective therapy for …
The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans
P Xue, E Sánchez-León, G Hu, CWJ Lee, B Black… - Msphere, 2024 - Am Soc Microbiol
… Connections between factors that regulate iron homeostasis … In this study, we identified
connections between iron … factor in the pathogenic fungus Cryptococcus neoformans. This fungus …
connections between iron … factor in the pathogenic fungus Cryptococcus neoformans. This fungus …
Defects in phosphate acquisition and storage influence virulence of Cryptococcus neoformans
M Kretschmer, E Reiner, G Hu, N Tam… - Infection and …, 2014 - Am Soc Microbiol
… Cryptococcosis is a fungal disease of humans caused by the basidiomycete yeast Cryptococcus
neoformans (1)… and characterized Cir1 as the master regulator of iron homeostasis in C. …
neoformans (1)… and characterized Cir1 as the master regulator of iron homeostasis in C. …
[HTML][HTML] Involvement of Mrs3/4 in mitochondrial iron transport and metabolism in Cryptococcus Neoformans
… Cryptococcus neoformans is a pathogenic fungus that infects humans to cause … iron
accumulation in mitochondria, and that iron deprivation within mitochondria induced …
accumulation in mitochondria, and that iron deprivation within mitochondria induced …
Iron acquisition in fungal pathogens of humans
… Additionally, the fungus Cryptococcus neoformans is a devastating agent of meningitis in
HIV/… iron permease FTR1 is also induced upon iron deprivation. Importantly, FTR1 in C. albicans…
HIV/… iron permease FTR1 is also induced upon iron deprivation. Importantly, FTR1 in C. albicans…
Role of a VPS41 homologue in starvation response, intracellular survival and virulence of Cryptococcus neoformans
X Liu, G Hu, J Panepinto… - Molecular …, 2006 - Wiley Online Library
… for normal growth of C. neoformans even under conditions of low iron availability and plays
no … Cell cycle arrest is a prominent response to nutrient deprivation of higher eukaryotes and …
no … Cell cycle arrest is a prominent response to nutrient deprivation of higher eukaryotes and …
Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi
J Pijuan, DF Moreno, G Yahya, M Moisa… - Microbial …, 2023 - Wiley Online Library
… with iron deprivation in slowing growth on some pathogenic fungi, by further inhibiting iron
… Cryptococcus neoformans is a human fungal pathogen that can cause meningoencephalitis …
… Cryptococcus neoformans is a human fungal pathogen that can cause meningoencephalitis …
Iron Deprivation Modulates the Exoproteome in Paracoccidioides brasiliensis
AF Souza, LL Pigosso, LOHS Silva… - Frontiers in Cellular …, 2022 - frontiersin.org
… is able to reduce iron, and the reductase activity is linked to ferric iron uptake … iron deprivation.
Of particular relevance is the fungus ability to use hemoglobin as the preferential host iron …
Of particular relevance is the fungus ability to use hemoglobin as the preferential host iron …