… from host proteins, while others appear to require a membrane-bound iron … Cryptococcus
neoformans to use host iron sources including transferrin and heme, and we identify an iron …

… In this study, we continued our analysis of the reductive iron uptake system in C. neoformans
… cerevisiae, Fet3 and the iron permease Ftr1 form a complex at the plasma membrane and …

… pathway of the opportunistic pathogen Cryptococcus neoformans. Here we studied iron
uptake directly, using 55 Fe in the presence of reductants. Uptake was linear with respect to time …

… In this review, we describe iron uptake and regulatory mechanisms in C. neoformans, in
comparison … As with other aspects of fungal biology, the analysis of iron-related functions in C. …

… were involved in iron uptake and … iron uptake and homeostasis play a key role in antifungal
susceptibility and could be used as novel targets for combination treatment of cryptococcosis…

… regulation of iron uptake pathways in C. neoformans is expanding and emerging themes
from recent work highlight the importance of mitochondria as a target organelle for iron delivery …

… This defense, too, is breached in immunocompromised patients who develop cryptococcosis.
We study iron uptake in C. neoformans in the hope that manipulations of iron availability …

… high-affinity iron uptake system in the pathogenesis of C. … neoformans could predominantly
use an iron uptake system … Although the reductive high-affinity iron uptake system mediated …

… involved in iron, copper, and zinc uptake and homeostasis in the fungal pathogens
Paracoccidioides brasiliensis, Cryptococcus neoformans var. grubii, and Cryptococcus gattii. …

… high-affinity iron uptake system is an important virulence determinant in C. neoformans and
C. … fumigatus, and this mechanism is employed by these two pathogens to acquire iron from …