… Studies in the fungal pathogen, Cryptococcus neoformans, have shown that loss of GlcCer
synthase activity results in complete loss of virulence in the mouse model. However, whether …

… Thus we assessed major virulence attributes (growth at 37C, melanin production on niger …
small blood vessels and airways, stimulating extensive mucin secretion, which was absent in …

… 1 week after infection (mucin staining; magnification, ×165). (H) Macrophages containing
many … neoformans polysaccharide can enhance IL-10 production by macrophages in vitro, and …

… In the present study, the reduced mucus production in the IL-33 −/− infected … mucus production
and survival extension. Of note, goblet cell hyperplasia and increased mucus production …

… the cryptococcal cells stained with mucin carmine (indicated with arrows; Scale bar: 20 μm).
… [34,50], the ELISA and IF data produced in this investigation demonstrated that in delivery of …

… Cryptococcus neoformans causes serious pulmonary and meningeal infections, particularly
… that the most important pathogenic constituent of C. neoformans identified so far is capsular …

… of the human fungal pathogen, Cryptococcus neoformans. Previously, we identified
Dectin-1 as a likely phagocytic receptor for C. neoformans spores through the use of soluble …

… CD4+ and CD8+ T cells are important for production of a … At 24 and 48 h, mucin and GXM
stains showed clusters of … Mucin and GXM staining demonstrated a marked increase in …

… anticryptococcal activity through production of nitric oxide. Clin … gamma-producing
Cryptococcus neoformans strain results in … mucin production in the lungs after pulmonary infection …

… Dectin-2 is postulated to induce Th2-type responses and IL-4-dependent mucin production
in the lungs following infection with Cn-D (20). The impact of Dectin-2 deficiency may also …