… TLRs), C-type lectin receptors, NOD-like receptors (NLRs), and soluble receptors. Additionally,
… will highlight critical cryptococcal PAMPs involved in the recognition of Cryptococcus. The …

… broncoepithelial cells to secrete mucin, which may lead … producing memory-phenotype 丁
cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans…

… than WT macrophages, with increased production of tumor necrosis factor (TNF) and
CCL5/RANTES and more efficient uptake and killing of C. neoformans . These findings suggest that …

… cause disease in humans are Cryptococcus neoformans and Cryptococcus gattii. These
pathogens can … have enhanced fungal uptake and killing and TNFα production in response to C. …

… Though the response to nitrosative stress has not been studied in Cryptococcus neoformans,
… It has been shown that macrophages produce nitric oxide in response to cryptococcal cells (…

… shown to elicit type I interferon production, and in turn these so-… This is particularly true of
Cryptococcus neoformans, a … ) infected patients, where it causes cryptococcal meningitis [13]. …

… amounts of mucus had deposits of … Cryptococcus sp. was made by demonstration of typical
yeast morphology, the presence of a capsule, growth at 37 C and urease production at 25 C …

… is a disease predominantly caused by the species Cryptococcus neoformans and C. gattii in
humans and other mammals … Melanin production by laccase is another virulence factor of C. …

… production from CD4 cells, promote clearance of Histoplasma capsulatum and Cryptococcus
neoformans … tissues and vasculature, while mucus and antimicrobial peptides further deter …

… Further investigation of the production of NO in ×i×o revealed … the mice showed identical
levels of NO production [16]. This … capsular material and:or airway mucus) than did controls (not …