… Microbial capsules play important roles in the lives of these microorganisms, providing … The
best characterized fungal capsule belongs to Cryptococcus neoformans. The capsule of this …

… The capsule is closely associated with the virulence of Cryptococcus neoformans. The
capsule inhibits phagocytosis by macrophages, monocytes, and neutrophils. Studies in our …

… Nevertheless, the capsule probably did not evolve for its role in pathogenesis. … CD4+ T
cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the …

… To assess the role of this putative transcriptional regulator in capsule formation, we replaced
the ADA2 genomic coding sequence with a nourseothricin-resistance marker (NAT) in the …

… Cryptococcus neoformans yeast cells visualized by India Ink … India Ink particles are excluded
from the dense PS capsule. A. … purpose of capsule lipids and their role in capsule structure …

… Cryptococcus neoformans is characterized by its ability to induce a distinct polysaccharide
capsule in … There is considerable evidence that the capsule plays a central role in allowing C. …

… Of these, Cryptococcus neoformans has emerged as an important cause of mortality in …
neoformans PKA1 gene product has a clear role in capsule production (33), sinces a pka1 …

… cryptococcal infections, such as meningitis. The capsule of Cryptococcus neoformans is …
To further investigate the role of the capsule in escape from the intravascular compartment, …

… The antiphagocytic polysaccharide capsule of the human fungal pathogen Cryptococcus
neoformans is a major virulence attribute. However, previous studies of the pleiotropic …

Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues in order to establish a human infection. We have identified the C. neoformans …