The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection

GJC Freitas, L Gouveia-Eufrasio, ECP Emidio… - Cells, 2022 - mdpi.com
Cryptococcus neoformans, cell size reduction (cell body ≤ 3 µm) is important for initial
adaptation during infection. This change … We investigated the transcriptional changes involved in …

The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host

TR O'Meara, W Xu, KM Selvig… - … and cellular biology, 2014 - Am Soc Microbiol
… To determine the transcription changes dependent on the pka1Δ mutation, the pka1Δ
mutant was incubated under conditions identical to those for strains used in prior transcriptome …

Remodeling of Global Transcription Patterns of Cryptococcus neoformans Genes Mediated by the Stress-Activated HOG Signaling Pathways

YJ Ko, YM Yu, GB Kim, GW Lee, PJ Maeng, S Kim… - Eukaryotic …, 2009 - Am Soc Microbiol
… ) were transcriptionally regulated with more than a twofold change. Half of the genes (289
genes) were osmotic SSR genes (Fig. 8), named as OsSR genes, and listed in Table S9 in the …

Transcriptional regulation by protein kinase A in Cryptococcus neoformans

G Hu, BR Steen, T Lian, AP Sham, N Tam… - PLoS …, 2007 - journals.plos.org
… in the fungal pathogen Cryptococcus neoformans. Conversely, … Among the myriad of
transcriptional changes in the mutants, … The transcriptional influence of PKA on these functions …

Transcription Factor Nrg1 Mediates Capsule Formation, Stress Response, and Pathogenesis in Cryptococcus neoformans

KL Cramer, QD Gerrald, CB Nichols, MS Price… - Eukaryotic …, 2006 - Am Soc Microbiol
… given the transcriptional changes in chitin and carbohydrate metabolism suggested by
the microarray data. Altered flocculation and cell adhesion are also often associated with …

RNA biology and the adaptation of Cryptococcus neoformans to host temperature and stress

ALM Bloom, JC Panepinto - Wiley Interdisciplinary Reviews …, 2014 - Wiley Online Library
… In addition, while analyzing the gene expression changes over a … transcription factor Mga2
was identified in this study), our data suggest that 3 h may be too long to observe the changes

[HTML][HTML] Identification of novel temperature-regulated genes in the human pathogen Cryptococcus neoformans using representational difference analysis

LKR e Silva, CC Staats, LS Goulart, LG Morello… - Research in …, 2008 - Elsevier
… We found conserved domains related to transcription factors … found in the jumonji family of
transcription factors, and a DNA … (relative fold change) that a selected gene is expressed in C. …

Posttranslational, Translational, and Transcriptional Responses to Nitric Oxide Stress in Cryptococcus neoformans: Implications for Virulence

TA Missall, ME Pusateri, MJ Donlin, KT Chambers… - Eukaryotic …, 2006 - Am Soc Microbiol
… In this study, we examine the proteomic and transcriptional response of C. neoformans to
nitric … variations and suggest that a large percentage of transcriptional changes correlate with …

Temperature-regulated transcription in the pathogenic fungus Cryptococcus neoformans

BR Steen, T Lian, S Zuyderduyn… - Genome …, 2002 - genome.cshlp.org
… Assuming that these changes in transcript levels reflect changes in the abundance of
histone proteins, our results indicate that growth temperature may exert a general influence on …

Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans

AN Hawkins, BF Determann, BN Nelson… - Frontiers in …, 2021 - frontiersin.org
neoformans exposure. Within permissive and non-permissive phagocytes, we discovered a
… as an indicator that C. neoformans leads to transcriptional changes which may contribute to …