DeepRescore: leveraging deep learning to improve peptide identification in immunopeptidomics

K Li, A Jain, A Malovannaya, B Wen, B Zhang - Proteomics, 2020 - Wiley Online Library
… the quality of the peptides identified by DeepRescore, we used MHC-peptide binding affinity
as a systematic and unbiased quantitative metric and three MHC-peptide binding prediction …

Sequence-based peptide identification, generation, and property prediction with deep learning: a review

X Chen, C Li, MT Bernards, Y Shi, Q Shao… - … Systems Design & …, 2021 - pubs.rsc.org
… In this review we discuss the general process of deep learning for peptide identification, …
Deep learning has shown excellent performance with representation learning and the deep

MSBooster: improving peptide identification rates using deep learning-based features

KL Yang, F Yu, GC Teo, K Li, V Demichev… - Nature …, 2023 - nature.com
… against sequences of candidate peptides using database search tools, … peptide-to-spectrum
matches using additional features incorporating deep learning-based predictions of peptide

DeepMSPeptide: peptide detectability prediction using deep learning

G Serrano, E Guruceaga, V Segura - Bioinformatics, 2020 - academic.oup.com
… of the peptides. In this manuscript, we present DeepMSPeptide, a bioinformatic tool that
uses a deep learning method to predict proteotypic peptides exclusively based on the peptide

Deep learning neural network tools for proteomics

JG Meyer - Cell Reports Methods, 2021 - cell.com
… for peptide property prediction and peptide/protein identification, provide perspective on
how deep learning solves the associated challenges, and contrast the different deep learning

DeepACP: a novel computational approach for accurate identification of anticancer peptides by deep learning algorithm

L Yu, R Jing, F Liu, J Luo, Y Li - Molecular Therapy-Nucleic Acids, 2020 - cell.com
… Therefore, we propose DeepACP, a deep learning method combined with the RNN model
and amino-acid character embedding for improving ACP prediction. When performed on the …

Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification

B Bulik-Sullivan, J Busby, CD Palmer, MJ Davis… - Nature …, 2019 - nature.com
peptides or tandem minigenes, or are only relevant to specific human leukocyte antigen (HLA)
alleles. We apply deep learning to a large (N = 74 patients) HLA peptideidentification of …

De novo peptide sequencing by deep learning

NH Tran, X Zhang, L Xin, B Shan… - Proceedings of the …, 2017 - National Acad Sciences
deep learning to de novo peptide sequencing and achieve major breakthroughs on this
well-studied problem. Deep learning … DeepNovo was able to identify peptides that could not be …

A deep-learning framework for multi-level peptide–protein interaction prediction

Y Lei, S Li, Z Liu, F Wan, T Tian, S Li, D Zhao… - Nature …, 2021 - nature.com
… Furthermore, we sought to decipher the underlying mechanisms of peptide–protein interactions
by identifying the peptide-binding residues. We showed that CAMP can accurately detect …

Prediction of peptide mass spectral libraries with machine learning

J Cox - Nature Biotechnology, 2023 - nature.com
… consideration when identifying the best … peptides is a more important factor than the size
of the search space. Another promising application of deep learning to the peptide identification