[PDF][PDF] Changes in the placenta and in the rat embryo caused by the demethylating agent 5-azacytidine
… In vitro experiments with 5azaC on gastrulating rat embryo … of DNA demethylation in the rat
embryonic development … different types of disorders during embryonic development such as …
embryonic development … different types of disorders during embryonic development such as …
Effects of a DNA demethylating agent-5-azacytidine-on testicular morphology during mouse embryo development
HE BULUT, Ö ÖZDEMIR… - Okajimas folia …, 1999 - jstage.jst.go.jp
… rat 6/c-myc cells. Hossain et al. (1997b) found that 5-azaC, a cytidine analogue, produced
apoptosis of fetal developing neuronal cells the day after injection of the agent into dams by …
apoptosis of fetal developing neuronal cells the day after injection of the agent into dams by …
Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells
K Tsuji-Takayama, T Inoue, Y Ijiri, T Otani… - Biochemical and …, 2004 - Elsevier
… The de novo methylation activity is essential for embryonic development as well as embryonic
… In this study, we investigated the effects of a demethylating agent, 5-azacytidine (5-AzaC), …
… In this study, we investigated the effects of a demethylating agent, 5-azacytidine (5-AzaC), …
Impact of 5‐azacytidine on rat decidual cell proliferation
… The DNA demethylating agent 5-azacytidine (5-azaC) has a teratogenic influence during
rat development influencing both the embryo and the placenta. Our aim was to investigate its …
rat development influencing both the embryo and the placenta. Our aim was to investigate its …
Deoxyribonucleic acid hypomethylation of male germ cells by mitotic and meiotic exposure to 5-azacytidine is associated with altered testicular histology
T Doerksen, G Benoit, JM Trasler - Endocrinology, 2000 - academic.oup.com
… rats with 5-azacytidine results in the demethylation of sperm … kinetics of spermatogenesis
in the rat, we were able to use … used here resulted in alterations in fertility and early embryo …
in the rat, we were able to use … used here resulted in alterations in fertility and early embryo …
The influence of demethylating agents on preimplantation development of mice
EL Patkin, ME Kustova, P Perticone - Zygote, 1998 - cambridge.org
… agents influence the proliferation of embryos depending on the stage of cleavage, and (b) Aza
… Effects of ethionine treatment of protein-synthesizing apparatus of rat liver 80 S ribosomes …
… Effects of ethionine treatment of protein-synthesizing apparatus of rat liver 80 S ribosomes …
Gastrulating rat embryo in a serum-free culture model: changes of development caused by teratogen 5-azacytidine
F Bulić-Jakuš, M Vlahović… - Alternatives to …, 1999 - journals.sagepub.com
… tion embryos (10). The method used in the present study involves cultivating 9.5-day-old rat
embryos, … Teratogenic effects of the demethylating agent 5-aza2deoxydytidine in the Swiss …
embryos, … Teratogenic effects of the demethylating agent 5-aza2deoxydytidine in the Swiss …
[PDF][PDF] Epigenetic deregulation through DNA demethylation seems not to interfere with the differentiation of epithelia from pre-gastrulating rat embryos in vitro
… in pre-gastrulating rat embryos cultivated in vitro under the influence of the demethylating
agent 5azacytidine (5azaC) was investigated. Eight-day-old Fisher rat embryos consisting of …
agent 5azacytidine (5azaC) was investigated. Eight-day-old Fisher rat embryos consisting of …
Cell death and cell cycle perturbation in the developmental toxicity of the demethylating agent, 5‐aza‐2′‐deoxycytidine
JM Rogers, BM Francis, KK Sulik, AJ Alles… - …, 1994 - Wiley Online Library
… 5-aza-2'-deoxycytidine (dAZA], a specific and potent demethylator of DNA, to pregnant mice
to determine its teratogenicity and effects on embryonic … of AZA has been studied in the rat (…
to determine its teratogenicity and effects on embryonic … of AZA has been studied in the rat (…
5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses
M Ueno, K Katayama, A Yasoshima… - Experimental and …, 2002 - Elsevier
… 5 of the pyrimidine ring. In this study, detailed histopathological changes were sequentially
examined in the rat fetal … in the rat embryo caused by the demethylating agent 5-azacytidine. …
examined in the rat fetal … in the rat embryo caused by the demethylating agent 5-azacytidine. …
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