… methylation profiles of zebrafish developing embryos and sperm by using two … developmental
stages. We find that a substantial portion of dsDMRs behave as developmental enhancers, …

… enhancer bookmarking during early embryonic development. Poised developmental enhancers
… During differentiation, appropriate developmental and signalling cues are able to rapidly …

… measure but reflect selected key studies in the field focusing on embryonic stem cells (ESCs).
For further information on enhancer and CTCF functions, we suggest these reviews (Ong …

… A recent study of mammalian embryonic stem cells revealed that several enhancers seem
to be protected from DNA methylation 113 , suggesting that specific mechanisms may prevent …

… ES cells with developmental enhancers we … as enhancers during early development. This
finding provides an unknown link between the gene regulatory networks of ES cells and early …

… candidate developmental enhancers in 20 h sea urchin embryos … also characterized in 12 h
embryos. The genomic profile of 3′ … other early embryo TREs, ME has distinct enhancer and …

… as bona fide enhancers and produced localized patterns of gene expression across the DV
axis of early embryos. The other set produced no expression in transgenic embryos, despite …

… developmental enhancers, providing a foundation for investigating the question of whether
… regions of the early embryo. As pSmads become activated in the vegetal embryonic cells (…

… of H3K27ac enrichment in the early embryo and that stage-specific … the embryonic epigenomes
associated with early zebrafish … -like protein on early developmental enhancers, thereby …

… enhancer interactome maps across ten mouse embryonic tissues for 935 bona fide developmental
enhancers … thousands of enhancer contacts and found that most enhancer loci display …