Aneuploidy and DNA methylation as mirrored features of early human embryo development

EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… but here, we consider the relationship of DNA methylation and aneuploidy in early human and
… enzymes or DNA methylation regulators are associated with developmental disorders and …

DNA methylation and the preservation of cell identity

O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
… the developmental roles of DNA methylation in various vertebrate model systems. It is now
evident that in certain contexts DNA methylation … the quantity of DNA methylation will merely …

[PDF][PDF] The role of DNA methylation in invertebrates: developmental regulation or genome defense?

A Regev, MJ Lamb, E Jablonka - Molecular Biology and Evolution, 1998 - researchgate.net
… , and (2) cytosine methylation is primarily a defense mechanism … We discuss the role of
DNA methylation in the evolution of … are important and primitive functions of DNA methylation. …

Notes on the role of dynamic DNA methylation in mammalian development

TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
… When Dnmt3L-null oocytes that are largely free of DNA methylation at single-copy sequences
are fertilized by wild-type sperm, developmental abnormalities in the resulting embryos …

Strategies for DNA methylation analysis in developmental studies

C Piperi, AG Papavassiliou - Development, growth & …, 2011 - Wiley Online Library
… Despite the intense research on distribution dynamics of DNA methylation among species,
we are just beginning to elucidate methylation patterns that may control gene expression, …

Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages

X Yang, B Hu, Y Hou, Y Qiao, R Wang, Y Chen, Y Qian… - Cell Research, 2018 - nature.com
… Importantly, we show that the key developmental genes are regulated by … developmental
plasticity in the embryonic cells, as well as the permanent restriction of ExE developmental

Programming of DNA methylation patterns

H Cedar, Y Bergman - Annual review of biochemistry, 2012 - annualreviews.org
DNA methylation represents … DNA methylation is erased in the blastocyst, and a bimodal
pattern is established anew at the time of implantation when the entire genome gets methylated

DNA methylation and developmental genes in lymphomagenesis—more questions than answers?

PH Kay, DV Spagnolo, J Taylor, M Ziman - Leukemia & lymphoma, 1997 - Taylor & Francis
… of DNA methylation and developmental genes in malignant lymphoproliferative diseases. …
of DNA methylation are remarkably diverse in cellular biology. For example, DNA methylation

Embryonic DNA methylation: insights from the genomics era

O Bogdanović… - Briefings in functional …, 2014 - academic.oup.com
… of how DNA methylation is remodeled during early vertebrate embryogenesis and highlighted
important differences in developmental … of the role of DNA methylation during vertebrate …

DNA methylation in genomic imprinting, development, and disease

M Paulsen, AC Ferguson‐Smith - The Journal of pathology, 2001 - Wiley Online Library
DNA methylation is also involved in X‐chromosome inactivation … DNA methylation can
regulate gene expression, using imprinted genes as examples. The molecular basis of methylation