[HTML][HTML] Chronological age prediction: developmental evaluation of DNA methylation-based machine learning models
… Epigenetic clock, a highly accurate age estimator based on DNA methylation (DNAm) level,
is the basis for predicting mortality/morbidity and elucidating the molecular mechanism of …
is the basis for predicting mortality/morbidity and elucidating the molecular mechanism of …
DNA methylation subpatterns at distinct regulatory regions in human early embryos
R Luo, C Bai, L Yang, Z Zheng, G Su… - Royal Society …, 2018 - royalsocietypublishing.org
… at different developmental stages had similar DNA methylation … -methylated states according
to the DNA methylation level of … were hypo-methylated in all the developmental stages. All …
to the DNA methylation level of … were hypo-methylated in all the developmental stages. All …
DNA methylation: shared and divergent features across eukaryotes
… to simply as DNA methylation, in … of DNA methylation may be more diverse and complex
than was previously appreciated. We summarize the current understanding of DNA methylation …
than was previously appreciated. We summarize the current understanding of DNA methylation …
DNA methylation dynamics during the mammalian life cycle
JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
… developmental DNA methylation at key promoters underpins Waddington's image of canalization
of cell fate, particularly, the early developmental … genomic and developmental contexts, …
of cell fate, particularly, the early developmental … genomic and developmental contexts, …
Dynamic DNA methylation: In the right place at the right time
… Here we review recent findings that delineate 5mC functions in developmental stages and
diverse genomic compartments as well as discuss the molecular mechanisms that connect …
diverse genomic compartments as well as discuss the molecular mechanisms that connect …
The emerging role of DNA methylation in epileptogenesis
… ) to cytosine nucleotides via a DNA methyltransferase enzyme. 5′‐… DNA methylation
dynamics broadly influence brain development, function, and aging. Aberrant DNA methylation …
dynamics broadly influence brain development, function, and aging. Aberrant DNA methylation …
Combinatorial identification of DNA methylation patterns over age in the human brain
… DNA methylation plays a key role in developmental processes, which is reflected in changing
methylation patterns at specific CpG sites over the lifetime of an individual. The underlying …
methylation patterns at specific CpG sites over the lifetime of an individual. The underlying …
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
… DNA methylation during later developmental stages and in tissues in which Zfp57 is not
expressed. Consequently, another KRAB-ZNF factor, ZNF274, emerged as a regulator of parent-…
expressed. Consequently, another KRAB-ZNF factor, ZNF274, emerged as a regulator of parent-…
DNA methylation in epigenetic control of gene expression
A Razin, B Kantor - Epigenetics and Chromatin, 2005 - Springer
… The three-way connection between DNA methylation, … DNA methylation and histone
modification are currently under investigation. DNA methylation is implicated in developmental …
modification are currently under investigation. DNA methylation is implicated in developmental …
[HTML][HTML] Leveraging epigenetics to examine differences in developmental trajectories of social attention: A proof-of-principle study of DNA methylation in infants with …
… phenotypic traits and DNA methylation levels in the … DNA methylation profiles at multiple
time-points in infant-sibling designs is a promising avenue to comprehend developmental …
time-points in infant-sibling designs is a promising avenue to comprehend developmental …