[HTML][HTML] Chronological age prediction: developmental evaluation of DNA methylation-based machine learning models

H Fan, Q Xie, Z Zhang, J Wang, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
… Epigenetic clock, a highly accurate age estimator based on DNA methylation (DNAm) level,
is the basis for predicting mortality/morbidity and elucidating the molecular mechanism of …

DNA methylation subpatterns at distinct regulatory regions in human early embryos

R Luo, C Bai, L Yang, Z Zheng, G Su… - Royal Society …, 2018 - royalsocietypublishing.org
… at different developmental stages had similar DNA methylation … -methylated states according
to the DNA methylation level of … were hypo-methylated in all the developmental stages. All …

DNA methylation: shared and divergent features across eukaryotes

RJ Schmitz, ZA Lewis, MG Goll - Trends in Genetics, 2019 - cell.com
… to simply as DNA methylation, in … of DNA methylation may be more diverse and complex
than was previously appreciated. We summarize the current understanding of DNA methylation

DNA methylation dynamics during the mammalian life cycle

JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
developmental DNA methylation at key promoters underpins Waddington's image of canalization
of cell fate, particularly, the early developmental … genomic and developmental contexts, …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… Here we review recent findings that delineate 5mC functions in developmental stages and
diverse genomic compartments as well as discuss the molecular mechanisms that connect …

The emerging role of DNA methylation in epileptogenesis

K Kobow, I Blümcke - Epilepsia, 2012 - Wiley Online Library
… ) to cytosine nucleotides via a DNA methyltransferase enzyme. 5′‐… DNA methylation
dynamics broadly influence brain development, function, and aging. Aberrant DNA methylation

Combinatorial identification of DNA methylation patterns over age in the human brain

B Torabi Moghadam, M Dabrowski, B Kaminska… - BMC …, 2016 - Springer
DNA methylation plays a key role in developmental processes, which is reflected in changing
methylation patterns at specific CpG sites over the lifetime of an individual. The underlying …

Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns

C Marchal, B Miotto - Journal of cellular physiology, 2015 - Wiley Online Library
DNA methylation during later developmental stages and in tissues in which Zfp57 is not
expressed. Consequently, another KRAB-ZNF factor, ZNF274, emerged as a regulator of parent-…

DNA methylation in epigenetic control of gene expression

A Razin, B Kantor - Epigenetics and Chromatin, 2005 - Springer
… The three-way connection between DNA methylation, … DNA methylation and histone
modification are currently under investigation. DNA methylation is implicated in developmental

[HTML][HTML] Leveraging epigenetics to examine differences in developmental trajectories of social attention: A proof-of-principle study of DNA methylation in infants with …

A Gui, EJH Jones, CCY Wong, E Meaburn, B Xia… - Infant Behavior and …, 2020 - Elsevier
… phenotypic traits and DNA methylation levels in the … DNA methylation profiles at multiple
time-points in infant-sibling designs is a promising avenue to comprehend developmental