… The sea urchin embryo is an important model system for developmental gene regulatory
network (… resolution of multiple gene products is required for constructing a developmental GRN. …

… We identify a class of GRN component, the kernels” of the network, which, because of their
developmental role and their particular internal structure, are most impervious to change. …

… To showcase the applicability of the orbital equivalence framework in these scenarios, we
will implement it within a well-known gene regulatory network, the repressilator (see Fig. 4A). …

… insights into the evolution of gene regulatory processes and their adaptive … network level.
Here, we review computational methods developed to study transcriptional regulatory networks …

… of the best characterized mammalian developmental systems. However, the field is still in
its infancy with regard to the reconstruction of gene regulatory networks and their interactions …

… compares portions of the gene regulatory networks underlying the specification of the … (B)
Comparison of portions of the underlying gene regulatory networks. The top diagram, …

… Key upstream genes, such as Pax3 and Pax7, Six1 and Six4, or Pitx2, participate in gene
regulatory networks at different sites of skeletal muscle formation. MicroRNAs also intervene, …

… the expression and function of genes in the underlying regulatory networks. We found that …
by differences in gene regulatory network architecture in different developmental contexts, as …

… an entire developmental pathway, we generated global gene … of regulatory elements
driving differential gene expression … We present a dynamic core regulatory network model for …

… plan is controlled by large networks of regulatory genes. A gene regulatory network that
controls the … Here we can see how an active cis-regulatory network produces the developmental …