… to investigate the role of imprinted gene expression in an established murine model of
developmental programming. Specifically we aimed to assess imprinted gene expression in the …

… growth and development. Next, I review salient evidence with regard to imprinted gene effects
on … and growth, and timing of developmental stages, to evaluate why and how imprinted …

… In this study, we have used an established model of developmental programming—… of
imprinted genes in the offspring. We find that although expression of some imprinted genes in liver …

… with consequences for development both before and after birth. Changes in expression of
imprinted genes, therefore, have major implications for developmental programming and may …

… of key developmental genes are subject to tissue-specific methylation during development.
Such methylation had previously been reported only for imprinted and X-inactivated genes. …

… Using the mouse as a model, we identify the imprinted gene Grb10 as a mediator of nutrient
supply and demand in the postnatal period. The combined actions of Grb10 expressed in …

… on imprinted genes. In females, imprints are acquired at different times before ovulation in
maturing oocytes [43]. A growing body of evidence suggests that epigenetic gene regulation is …

… the paternal epigenetic programme to generate a relatively naïve transcriptionally silent
chromatin, which is a prelude to installation of the zygotic developmental programme that occurs …

… It follows that the imprinted genes must be differently … gene inactivation in preimplantation
embryos, and differential methylation in the gametes as a primary cause of imprinted gene …

… of developmental programming and result in permanent changes in the expression patterns
of particular genes… epigenetic changes to genes affecting kidney development do occur, are …