… fraction consists mostly of the glial cells (see above), we referred to the DM sites with
higher DNA methylation in neuronal versus nonneuronal cells as ‘glial undermethylated’ (GUM) …

… in mCpG and mCpH patterns between neuronal and glial cell populations in human and
rodent brains (24,36,37). A recent study in the adult mouse cortex, which used ‘nuclei tagged in …

… in glial cells to capture relevant molecular changes underlying MS neuropathology. We profiled
DNA methylation in nuclei of non-neuronal cells, … (n = 8) in comparison to white matter of …

… GE in a cell specific manner and ii) that differential methylation (DM) in neurons and glial cells
… A comparison of our results to those from peripheral blood of TLE patients [55], reveals 15 …

… to survey differences in DNA methylation between these two cell … importance of cell
type-specific differences in CpG methylation, … This finding is consistent with the role of glial cells as …

… Global DNA methylation levels in MIO-M1 cells. Global DNA methylation as measured by
the production of 5-methylcytosine (5-mC) under different stimuli during 24 h in MIO-M1 cells. …

… differential DNA methylation analysis was carried out separately for neuronal and glial cells,
… for neurons, while there was a marked difference in the glia. In the neuronal fraction, 115 …

… A comparison of our study with previous tissue-… and glia cell-type separation and DNA
methylation profiling. b Cluster analysis on complete data shows full separation of neuron and glia …

… mation on glial cell responses to DNA damaging agents. First, following exposure to MNU,
the formation of alkylation damage in mtDNA of cultured glial cells is not significantly different. …

… the development and cellular function within the brain. For example, changes in DNA
methylation are associated with neuronal and glial differentiation from neural stem cells (Takizawa …